Abstract
Background: In clinical use, topical diclofenac, a nonsteroidal antiinflammatory, was found to be remarkably effective as an analgesic. A trial was therefore conducted to quantify and compare this effect with that of other drugs commonly used after posterior segment surgery. Methods: A single-blind, randomized study of 37 patients undergoing posterior segment surgery was conducted. On the day of surgery and for 30 days thereafter, one group received topical diclofenac 0.1% and one group received topical betamethasone 0.1%. Pain intensity was assessed by two standard psychologic tests, the McGill Pain Questionnaire (MPQ) and Scott’s Visual Analogic Scale (VAS). Results: The group receiving diclofenac had significantly lower pain scores on the MPQ at days 1 and 15 (P <0.05 and P <0.03, respectively). The VAS scores were also statistically lower for this group on day 15 (P <0.03). Conclusion: Topical diclofenac 0.1% has greater analgesic action than topical betamethasone 0.1% without the side effects of steroids, and may be useful after posterior segment surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 34-36 |
| Number of pages | 3 |
| Journal | Retina |
| Volume | 15 |
| Issue number | 1 |
| Publication status | Published - 1995 |
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Keywords
- Analgesic effect
- Betamethasone
- Diclofenac
- McGill pain questionnaire
- Posterior segment surgery
- Visual analogic scale
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
Cite this
Analgesic effect of topical diclofenac versus betamethasone after posterior segment surgery. / Lesnoni, G.; Coppe, A. M.; Manni, G.; Billi, B.; Stirpe, M.
In: Retina, Vol. 15, No. 1, 1995, p. 34-36.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Analgesic effect of topical diclofenac versus betamethasone after posterior segment surgery
AU - Lesnoni, G.
AU - Coppe, A. M.
AU - Manni, G.
AU - Billi, B.
AU - Stirpe, M.
PY - 1995
Y1 - 1995
N2 - Background: In clinical use, topical diclofenac, a nonsteroidal antiinflammatory, was found to be remarkably effective as an analgesic. A trial was therefore conducted to quantify and compare this effect with that of other drugs commonly used after posterior segment surgery. Methods: A single-blind, randomized study of 37 patients undergoing posterior segment surgery was conducted. On the day of surgery and for 30 days thereafter, one group received topical diclofenac 0.1% and one group received topical betamethasone 0.1%. Pain intensity was assessed by two standard psychologic tests, the McGill Pain Questionnaire (MPQ) and Scott’s Visual Analogic Scale (VAS). Results: The group receiving diclofenac had significantly lower pain scores on the MPQ at days 1 and 15 (P <0.05 and P <0.03, respectively). The VAS scores were also statistically lower for this group on day 15 (P <0.03). Conclusion: Topical diclofenac 0.1% has greater analgesic action than topical betamethasone 0.1% without the side effects of steroids, and may be useful after posterior segment surgery.
AB - Background: In clinical use, topical diclofenac, a nonsteroidal antiinflammatory, was found to be remarkably effective as an analgesic. A trial was therefore conducted to quantify and compare this effect with that of other drugs commonly used after posterior segment surgery. Methods: A single-blind, randomized study of 37 patients undergoing posterior segment surgery was conducted. On the day of surgery and for 30 days thereafter, one group received topical diclofenac 0.1% and one group received topical betamethasone 0.1%. Pain intensity was assessed by two standard psychologic tests, the McGill Pain Questionnaire (MPQ) and Scott’s Visual Analogic Scale (VAS). Results: The group receiving diclofenac had significantly lower pain scores on the MPQ at days 1 and 15 (P <0.05 and P <0.03, respectively). The VAS scores were also statistically lower for this group on day 15 (P <0.03). Conclusion: Topical diclofenac 0.1% has greater analgesic action than topical betamethasone 0.1% without the side effects of steroids, and may be useful after posterior segment surgery.
KW - Analgesic effect
KW - Betamethasone
KW - Diclofenac
KW - McGill pain questionnaire
KW - Posterior segment surgery
KW - Visual analogic scale
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UR - http://www.scopus.com/inward/citedby.url?scp=0028840075&partnerID=8YFLogxK
M3 - Article
C2 - 7754246
AN - SCOPUS:0028840075
VL - 15
SP - 34
EP - 36
JO - Retina
JF - Retina
SN - 0275-004X
IS - 1
ER -