TY - JOUR
T1 - Analysis of 21 X-chromosomal STRs in an Algerian population sample
AU - Bekada, Asmahan
AU - Benhamamouch, Soraya
AU - Boudjema, Abdallah
AU - Fodil, Mustapha
AU - Menegon, Silvia
AU - Torre, Carlo
AU - Robino, Carlo
PY - 2010/7
Y1 - 2010/7
N2 - Twenty-one X-chromosomal short tandem repeat loci, including the six clusters of linked markers DXS10148-DXS10135-DXS8378 (Xp22), DXS7132-DXS10074-DXS10079 (Xq12), DXS6801-DXS6809-DXS6789 (Xq21), DXS7424-DXS101 (Xq22), DXS10103-HPRTB-DXS10101 (Xq26), DXS8377-DXS10146-DXS10134-DXS7423- DXS10011 (Xq28), and the loci DXS6800 and GATA172D05 were typed in a northwestern Algerian population sample (n∈=∈210; 104 men and 106 women). Allele and haplotype frequencies were calculated. No evidence of linkage disequilibrium was observed between pairs of loci within clusters of linked markers. At locus DXS10148, sequence analysis of a subset of alleles displaying unusual amplicon length (≥ 36 repeat units) and anomalous electrophoretic mobility showed that this marker has a complex molecular structure with different repeat variants within alleles of identical amplicon size.
AB - Twenty-one X-chromosomal short tandem repeat loci, including the six clusters of linked markers DXS10148-DXS10135-DXS8378 (Xp22), DXS7132-DXS10074-DXS10079 (Xq12), DXS6801-DXS6809-DXS6789 (Xq21), DXS7424-DXS101 (Xq22), DXS10103-HPRTB-DXS10101 (Xq26), DXS8377-DXS10146-DXS10134-DXS7423- DXS10011 (Xq28), and the loci DXS6800 and GATA172D05 were typed in a northwestern Algerian population sample (n∈=∈210; 104 men and 106 women). Allele and haplotype frequencies were calculated. No evidence of linkage disequilibrium was observed between pairs of loci within clusters of linked markers. At locus DXS10148, sequence analysis of a subset of alleles displaying unusual amplicon length (≥ 36 repeat units) and anomalous electrophoretic mobility showed that this marker has a complex molecular structure with different repeat variants within alleles of identical amplicon size.
KW - Algeria
KW - DXS10148
KW - Haplotype
KW - Linkage disequilibrium
KW - Short tandem repeat
KW - X chromosome
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U2 - 10.1007/s00414-009-0397-9
DO - 10.1007/s00414-009-0397-9
M3 - Article
C2 - 20012442
AN - SCOPUS:77954539262
VL - 124
SP - 287
EP - 294
JO - International Journal of Legal Medicine
JF - International Journal of Legal Medicine
SN - 0937-9827
IS - 4
ER -