Analysis of 21 X-chromosomal STRs in an Algerian population sample

Asmahan Bekada, Soraya Benhamamouch, Abdallah Boudjema, Mustapha Fodil, Silvia Menegon, Carlo Torre, Carlo Robino

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Twenty-one X-chromosomal short tandem repeat loci, including the six clusters of linked markers DXS10148-DXS10135-DXS8378 (Xp22), DXS7132-DXS10074-DXS10079 (Xq12), DXS6801-DXS6809-DXS6789 (Xq21), DXS7424-DXS101 (Xq22), DXS10103-HPRTB-DXS10101 (Xq26), DXS8377-DXS10146-DXS10134-DXS7423- DXS10011 (Xq28), and the loci DXS6800 and GATA172D05 were typed in a northwestern Algerian population sample (n∈=∈210; 104 men and 106 women). Allele and haplotype frequencies were calculated. No evidence of linkage disequilibrium was observed between pairs of loci within clusters of linked markers. At locus DXS10148, sequence analysis of a subset of alleles displaying unusual amplicon length (≥ 36 repeat units) and anomalous electrophoretic mobility showed that this marker has a complex molecular structure with different repeat variants within alleles of identical amplicon size.

Original languageEnglish
Pages (from-to)287-294
Number of pages8
JournalInternational Journal of Legal Medicine
Volume124
Issue number4
DOIs
Publication statusPublished - Jul 2010

Fingerprint

Alleles
Linkage Disequilibrium
Molecular Structure
Gene Frequency
Microsatellite Repeats
Haplotypes
Population
Sequence Analysis

Keywords

  • Algeria
  • DXS10148
  • Haplotype
  • Linkage disequilibrium
  • Short tandem repeat
  • X chromosome

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Bekada, A., Benhamamouch, S., Boudjema, A., Fodil, M., Menegon, S., Torre, C., & Robino, C. (2010). Analysis of 21 X-chromosomal STRs in an Algerian population sample. International Journal of Legal Medicine, 124(4), 287-294. https://doi.org/10.1007/s00414-009-0397-9

Analysis of 21 X-chromosomal STRs in an Algerian population sample. / Bekada, Asmahan; Benhamamouch, Soraya; Boudjema, Abdallah; Fodil, Mustapha; Menegon, Silvia; Torre, Carlo; Robino, Carlo.

In: International Journal of Legal Medicine, Vol. 124, No. 4, 07.2010, p. 287-294.

Research output: Contribution to journalArticle

Bekada, A, Benhamamouch, S, Boudjema, A, Fodil, M, Menegon, S, Torre, C & Robino, C 2010, 'Analysis of 21 X-chromosomal STRs in an Algerian population sample', International Journal of Legal Medicine, vol. 124, no. 4, pp. 287-294. https://doi.org/10.1007/s00414-009-0397-9
Bekada A, Benhamamouch S, Boudjema A, Fodil M, Menegon S, Torre C et al. Analysis of 21 X-chromosomal STRs in an Algerian population sample. International Journal of Legal Medicine. 2010 Jul;124(4):287-294. https://doi.org/10.1007/s00414-009-0397-9
Bekada, Asmahan ; Benhamamouch, Soraya ; Boudjema, Abdallah ; Fodil, Mustapha ; Menegon, Silvia ; Torre, Carlo ; Robino, Carlo. / Analysis of 21 X-chromosomal STRs in an Algerian population sample. In: International Journal of Legal Medicine. 2010 ; Vol. 124, No. 4. pp. 287-294.
@article{370a95e1230748f59c59bf6116c7166b,
title = "Analysis of 21 X-chromosomal STRs in an Algerian population sample",
abstract = "Twenty-one X-chromosomal short tandem repeat loci, including the six clusters of linked markers DXS10148-DXS10135-DXS8378 (Xp22), DXS7132-DXS10074-DXS10079 (Xq12), DXS6801-DXS6809-DXS6789 (Xq21), DXS7424-DXS101 (Xq22), DXS10103-HPRTB-DXS10101 (Xq26), DXS8377-DXS10146-DXS10134-DXS7423- DXS10011 (Xq28), and the loci DXS6800 and GATA172D05 were typed in a northwestern Algerian population sample (n∈=∈210; 104 men and 106 women). Allele and haplotype frequencies were calculated. No evidence of linkage disequilibrium was observed between pairs of loci within clusters of linked markers. At locus DXS10148, sequence analysis of a subset of alleles displaying unusual amplicon length (≥ 36 repeat units) and anomalous electrophoretic mobility showed that this marker has a complex molecular structure with different repeat variants within alleles of identical amplicon size.",
keywords = "Algeria, DXS10148, Haplotype, Linkage disequilibrium, Short tandem repeat, X chromosome",
author = "Asmahan Bekada and Soraya Benhamamouch and Abdallah Boudjema and Mustapha Fodil and Silvia Menegon and Carlo Torre and Carlo Robino",
year = "2010",
month = "7",
doi = "10.1007/s00414-009-0397-9",
language = "English",
volume = "124",
pages = "287--294",
journal = "International Journal of Legal Medicine",
issn = "0937-9827",
publisher = "Springer",
number = "4",

}

TY - JOUR

T1 - Analysis of 21 X-chromosomal STRs in an Algerian population sample

AU - Bekada, Asmahan

AU - Benhamamouch, Soraya

AU - Boudjema, Abdallah

AU - Fodil, Mustapha

AU - Menegon, Silvia

AU - Torre, Carlo

AU - Robino, Carlo

PY - 2010/7

Y1 - 2010/7

N2 - Twenty-one X-chromosomal short tandem repeat loci, including the six clusters of linked markers DXS10148-DXS10135-DXS8378 (Xp22), DXS7132-DXS10074-DXS10079 (Xq12), DXS6801-DXS6809-DXS6789 (Xq21), DXS7424-DXS101 (Xq22), DXS10103-HPRTB-DXS10101 (Xq26), DXS8377-DXS10146-DXS10134-DXS7423- DXS10011 (Xq28), and the loci DXS6800 and GATA172D05 were typed in a northwestern Algerian population sample (n∈=∈210; 104 men and 106 women). Allele and haplotype frequencies were calculated. No evidence of linkage disequilibrium was observed between pairs of loci within clusters of linked markers. At locus DXS10148, sequence analysis of a subset of alleles displaying unusual amplicon length (≥ 36 repeat units) and anomalous electrophoretic mobility showed that this marker has a complex molecular structure with different repeat variants within alleles of identical amplicon size.

AB - Twenty-one X-chromosomal short tandem repeat loci, including the six clusters of linked markers DXS10148-DXS10135-DXS8378 (Xp22), DXS7132-DXS10074-DXS10079 (Xq12), DXS6801-DXS6809-DXS6789 (Xq21), DXS7424-DXS101 (Xq22), DXS10103-HPRTB-DXS10101 (Xq26), DXS8377-DXS10146-DXS10134-DXS7423- DXS10011 (Xq28), and the loci DXS6800 and GATA172D05 were typed in a northwestern Algerian population sample (n∈=∈210; 104 men and 106 women). Allele and haplotype frequencies were calculated. No evidence of linkage disequilibrium was observed between pairs of loci within clusters of linked markers. At locus DXS10148, sequence analysis of a subset of alleles displaying unusual amplicon length (≥ 36 repeat units) and anomalous electrophoretic mobility showed that this marker has a complex molecular structure with different repeat variants within alleles of identical amplicon size.

KW - Algeria

KW - DXS10148

KW - Haplotype

KW - Linkage disequilibrium

KW - Short tandem repeat

KW - X chromosome

UR - http://www.scopus.com/inward/record.url?scp=77954539262&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954539262&partnerID=8YFLogxK

U2 - 10.1007/s00414-009-0397-9

DO - 10.1007/s00414-009-0397-9

M3 - Article

C2 - 20012442

AN - SCOPUS:77954539262

VL - 124

SP - 287

EP - 294

JO - International Journal of Legal Medicine

JF - International Journal of Legal Medicine

SN - 0937-9827

IS - 4

ER -