Analysis of candidate genes on chromosomes 5q and 19p in celiac disease

Anna Latiano, Barbara Mora, Margherita Bonamico, Francesca Megiorni, Maria Cristina Mazzilli, Salvatore Cucchiara, Orazio Palmieri, Maria Rosa Valvano, Vito Annese

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND AND AIM: Celiac disease (CD) is a multifactorial disease with involvement of both environmental and genetic susceptibility factors. The HLA-DQ loci account for 2000 CD patients and 4000 control individuals) question the role of MYO9B at the CELIAC4 locus as a disease-causing gene. Moreover, none of the investigated SNPs explain the linkage at the CELIAC2 locus.

Original languageEnglish
Pages (from-to)180-186
Number of pages7
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume45
Issue number2
DOIs
Publication statusPublished - Aug 2007

Keywords

  • Celiac disease
  • Human leukocyte antigen
  • Inflammatory bowel disease
  • MYO9B
  • Organic cation transporter
  • Single nucleotide polymorphism

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)
  • Gastroenterology
  • Histology
  • Pediatrics, Perinatology, and Child Health

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