Analysis of Circulating Mediators of Bone Remodeling in Prader-Willi Syndrome

G Brunetti, G Grugni, L Piacente, M Delvecchio, A Ventura, P Giordano, M Grano, G D'Amato, D Laforgia, A Crinò, M F Faienza

Research output: Contribution to journalArticle

Abstract

We tested the hypothesis that the levels of bone remodeling mediators may be altered in Prader-Willi syndrome (PWS). We assessed RANKL, OPG, sclerostin, DKK-1 serum levels, and bone metabolism markers in 12 PWS children (7.8 ± 4.3 years), 14 PWS adults (29.5 ± 7.2 years), and 31 healthy controls matched for sex and age. Instrumental parameters of bone mineral density (BMD) were also evaluated. Lumbar spine BMD Z-scores were reduced in PWS children (P 
Original languageItalian
Pages (from-to)635-643
Number of pages9
JournalCalcified Tissue International
Volume102
Issue number6
DOIs
Publication statusPublished - Jun 2018

Cite this

Analysis of Circulating Mediators of Bone Remodeling in Prader-Willi Syndrome. / Brunetti, G; Grugni, G; Piacente, L; Delvecchio, M; Ventura, A; Giordano, P; Grano, M; D'Amato, G; Laforgia, D; Crinò, A; Faienza, M F.

In: Calcified Tissue International, Vol. 102, No. 6, 06.2018, p. 635-643.

Research output: Contribution to journalArticle

Brunetti, G, Grugni, G, Piacente, L, Delvecchio, M, Ventura, A, Giordano, P, Grano, M, D'Amato, G, Laforgia, D, Crinò, A & Faienza, MF 2018, 'Analysis of Circulating Mediators of Bone Remodeling in Prader-Willi Syndrome', Calcified Tissue International, vol. 102, no. 6, pp. 635-643. https://doi.org/10.1007/s00223-017-0376-y
Brunetti, G ; Grugni, G ; Piacente, L ; Delvecchio, M ; Ventura, A ; Giordano, P ; Grano, M ; D'Amato, G ; Laforgia, D ; Crinò, A ; Faienza, M F. / Analysis of Circulating Mediators of Bone Remodeling in Prader-Willi Syndrome. In: Calcified Tissue International. 2018 ; Vol. 102, No. 6. pp. 635-643.
@article{c3e3952020174cd5971a2c067a499dd1,
title = "Analysis of Circulating Mediators of Bone Remodeling in Prader-Willi Syndrome",
abstract = "We tested the hypothesis that the levels of bone remodeling mediators may be altered in Prader-Willi syndrome (PWS). We assessed RANKL, OPG, sclerostin, DKK-1 serum levels, and bone metabolism markers in 12 PWS children (7.8 ± 4.3 years), 14 PWS adults (29.5 ± 7.2 years), and 31 healthy controls matched for sex and age. Instrumental parameters of bone mineral density (BMD) were also evaluated. Lumbar spine BMD Z-scores were reduced in PWS children (P ",
author = "G Brunetti and G Grugni and L Piacente and M Delvecchio and A Ventura and P Giordano and M Grano and G D'Amato and D Laforgia and A Crin{\`o} and Faienza, {M F}",
year = "2018",
month = "6",
doi = "10.1007/s00223-017-0376-y",
language = "Italian",
volume = "102",
pages = "635--643",
journal = "Calcified Tissue International",
issn = "0171-967X",
publisher = "Springer New York",
number = "6",

}

TY - JOUR

T1 - Analysis of Circulating Mediators of Bone Remodeling in Prader-Willi Syndrome

AU - Brunetti, G

AU - Grugni, G

AU - Piacente, L

AU - Delvecchio, M

AU - Ventura, A

AU - Giordano, P

AU - Grano, M

AU - D'Amato, G

AU - Laforgia, D

AU - Crinò, A

AU - Faienza, M F

PY - 2018/6

Y1 - 2018/6

N2 - We tested the hypothesis that the levels of bone remodeling mediators may be altered in Prader-Willi syndrome (PWS). We assessed RANKL, OPG, sclerostin, DKK-1 serum levels, and bone metabolism markers in 12 PWS children (7.8 ± 4.3 years), 14 PWS adults (29.5 ± 7.2 years), and 31 healthy controls matched for sex and age. Instrumental parameters of bone mineral density (BMD) were also evaluated. Lumbar spine BMD Z-scores were reduced in PWS children (P 

AB - We tested the hypothesis that the levels of bone remodeling mediators may be altered in Prader-Willi syndrome (PWS). We assessed RANKL, OPG, sclerostin, DKK-1 serum levels, and bone metabolism markers in 12 PWS children (7.8 ± 4.3 years), 14 PWS adults (29.5 ± 7.2 years), and 31 healthy controls matched for sex and age. Instrumental parameters of bone mineral density (BMD) were also evaluated. Lumbar spine BMD Z-scores were reduced in PWS children (P 

U2 - 10.1007/s00223-017-0376-y

DO - 10.1007/s00223-017-0376-y

M3 - Articolo

VL - 102

SP - 635

EP - 643

JO - Calcified Tissue International

JF - Calcified Tissue International

SN - 0171-967X

IS - 6

ER -