Analysis of intraocular lens surface adhesiveness by atomic force microscopy

Marco Lombardo, Giovanni Carbone, Giuseppe Lombardo, Maria P. De Santo, Riccardo Barberi

Research output: Contribution to journalArticlepeer-review


Purpose: To analyze intraocular lens (IOL) optic surface adhesiveness using atomic force microscopy (AFM). Setting: LiCryL Laboratory, University of Calabria, Rende, Italy. Methods: The surface adhesive properties of poly(methyl methacrylate) (PMMA), silicone, hydrophilic acrylic, and hydrophobic acrylic IOLs were evaluated by AFM. Analysis was performed at room temperature (21°C) in a liquid environment using the force-versus-distance mode of a commercial instrument (NanoScope III). Measurements were acquired with rectangular silicon cantilevers of a nominal elastic constant of 10 Newton/m. The nominal value of the tip's radius of curvature was 1 μm, and the scanning speed during the acquisitions ranged from 10 to 400 nm/s. Results: The adhesion force measurements showed different characteristics for the various types of IOLs (P

Original languageEnglish
Pages (from-to)1266-1272
Number of pages7
JournalJournal of Cataract and Refractive Surgery
Issue number7
Publication statusPublished - Jul 2009

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Surgery


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