Analysis of JC virus genotype distribution and transcriptional control region rearrangements in human immunodeficiency virus-positive progressive multifocal leukoencephalopathy patients with and without highly active antiretroviral treatment

Pasquale Ferrante, Serena Delbue, Elisabetta Pagani, Roberta Mancuso, Angela Marzocchetti, Elisa Borghi, Renato Maserati, Arabella Bestetti, Paola Cinque

Research output: Contribution to journalArticlepeer-review

Abstract

After the introduction of highly active antiretroviral therapy (HAART), the incidence of many acquired immunodeficiency syndrome (AIDS)-related opportunistic infections, but not of progressive multifocal leukoencephalopathy (PML), has been dramatically decreased. However, it has been shown that about 50% of the HAART-treated PML patients had a significantly prolonged (>6 months) survival time, in comparison to the short (

Original languageEnglish
Pages (from-to)42-46
Number of pages5
JournalJournal of NeuroVirology
Volume9
Issue numberSUPPL. 1
Publication statusPublished - 2003

Keywords

  • HAART treatment
  • JCV genomic organization
  • Progressive multifocal leukoencephalopathy (PML)

ASJC Scopus subject areas

  • Virology
  • Clinical Neurology

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