Analisi dell'esposizione professionale ad asbesto dei casi di mesotelioma Registrati in Romagna (1986-1998)

Translated title of the contribution: Analysis of occupational exposure to asbestos among mesothelioma cases registered in the Romagna Region of Italy (1986-1998)

M. Solaroli, M. G. Valentini, M. A. Geminiani, D. Baldisserri, R. Rambaldi, T. Samorè, M. Sintoni, C. Bissi, L. Fabbri, G. Bertazzini, I. Casadio, G. Focaccia, F. Falcini, D. Amadori, L. Bucchi

Research output: Contribution to journalArticle

Abstract

The aim of this study was to evaluate the prevalence and major correlates of occupational exposure to asbestos among the 125 cases of mesothelioma of the pleura, peritoneum, and pericardium registered in the Romagna Region of Italy between 1986 and 1998. Adequate occupational information was obtained for 122 (98%) cases. Among these, the male:female ratio was 81:41 (2.0), the median age was 68 years (range, 25-92), and the pleural location accounted for 96 (79%) cases. According to job history, 61 (50%) cases had had definite (23), probable (12), and possible (26) occupational exposure to asbestos. The probability (multiple logistic regression estimate) was greater for males (odds ratio, 10.8) but decreased for cases with mesothelioma of the peritoneum and pericardium (0.21) as well as those above the median age (0.38). Time period, residence, mode of diagnosis (histology, cytology, other), source of information (patient, wife/husband, others), and smoking habits exerted no independent effect. For 35 (57%) cases, occupational exposure was related to asbestos pollution of the workplace and not to the specific work task. Cases with definite, probable, and possible occupational exposure showed no significant difference in the distribution (Kruskal-Wallis test) by year of initial employment at risk, duration of exposure, and latency (median, 36 years). Occupational exposure occurred in a total of 22 workplaces. Three of these accounted for 21 (34%) cases. Multiple (≥2) cases (total 27 or 44%) were observed in six workplaces.

Original languageItalian
Pages (from-to)575-586
Number of pages12
JournalMedicina del Lavoro
Volume91
Issue number6
Publication statusPublished - 2000

    Fingerprint

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Solaroli, M., Valentini, M. G., Geminiani, M. A., Baldisserri, D., Rambaldi, R., Samorè, T., Sintoni, M., Bissi, C., Fabbri, L., Bertazzini, G., Casadio, I., Focaccia, G., Falcini, F., Amadori, D., & Bucchi, L. (2000). Analisi dell'esposizione professionale ad asbesto dei casi di mesotelioma Registrati in Romagna (1986-1998). Medicina del Lavoro, 91(6), 575-586.