Analisi delle recidive dopo trattamento conservativo del carcinoma mammario.

Translated title of the contribution: Analysis of recurrences following conservative treatment of breast carcinoma

A. Rigon, L. Friso, O. Lora, M. Pignataro, F. Berti, R. Mazzarotto, F. Simonato, F. Calzavara

Research output: Contribution to journalArticle

Abstract

In the conservative treatment of early breast cancer, great attention must be paid to define the prognostic factors correlated with the local recurrence rate. The goal is to customize surgery, radiotherapy and chemotherapy to the risk predicted in every single patient. To investigate the impact of some prognostic factors in a group of patients treated with homogeneous treatment schedules, 251 women with UICC stage I or II breast cancer were examined in the Padua Radiotherapy Department from 1988 to 1990. All patients underwent conservative surgery consisting in quadrantectomy, axillary node dissection and radiotherapy. During a median follow-up period of 49.2 months, 12 patients presented a breast relapse (4.8%). In 4 patients the relapse occurred in the same quandrant as the primary lesion, whereas a different quadrant was involved in the other 8 patients. The relapse rate in women under 60 was 5% and 4.7% in older patients, with p = 0.73. In pT1 patients, the relapse rate was 4.5% and in pT2 patients it was 7.9% (p = 0.37). No significant difference was observed between pN- and pN+ patients (4.5% vs. 6.25%, p = 0.37). In our series, none of the studied factors significantly influenced breast relapse rates. The number of patients may be too little relative to the low rate of relapses. However, an unfavorable trend was observed in the patients under 60, in pT2 or pN+ patients, or in the patients with positive or unknown surgical margins.

Translated title of the contributionAnalysis of recurrences following conservative treatment of breast carcinoma
Original languageItalian
Pages (from-to)794-796
Number of pages3
JournalRadiologia Medica
Volume90
Issue number6
Publication statusPublished - Dec 1995

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Rigon, A., Friso, L., Lora, O., Pignataro, M., Berti, F., Mazzarotto, R., Simonato, F., & Calzavara, F. (1995). Analisi delle recidive dopo trattamento conservativo del carcinoma mammario. Radiologia Medica, 90(6), 794-796.