Abstract
The γ-chain structure of a homozygote for HPFH Negro type, previously described by Acquaye and co-workers, and of 3 heterozygotes of the same family has been evaluated.Gγ andAγ chains were present in a ratio of fetal type (7/3) in the homozygote and in ratios of 2/3 and 1/1 in the heterozygotes, in agreement with data of the literature.Tγ chains were absent in all the cases. Our results, compared with those previously reported for Negro and Greek HPFH, suggest that theTγ gene is never linked with the HPFH determinant.
Original language | English |
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Pages (from-to) | 146-150 |
Number of pages | 5 |
Journal | Acta Haematologica |
Volume | 63 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1980 |
Keywords
- Hb F
- HPFH Negro type
- γ-Chain composition
ASJC Scopus subject areas
- Hematology