Analysis of the factors affecting auxological response to GnRH agonist treatment and final height outcome in girls with idiopathic central precocious puberty

Teresa Arrigo, Mariangela Cisternino, Fiorella Galluzzi, Silvano Bertelloni, Anna Maria Pasquino, Franco Antoniazzi, Patrizia Borrelli, Giuseppe Crisafulli, Malgorzata Wasniewska, Filippo De Luca

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Abstract

The aim of this retrospective study was to analyze the factors which affected the auxological response to GnRH agonist treatment and the final height (FH) outcome in 71 girls with idiopathic and truly precocious (onset before 8 years) central puberty (CTPP) who had been treated with the same therapy protocol (Decapeptyl Depot, 60 μg/kg i.m. every 28 days) for at least 2 years (since 7.0 ± 1.3 (S.D.) years of age) and followed until puberty was completed and FH was reached. During the entire treatment period we observed: (a) a decrease of height standard deviation scores (SDS) (from 1.5 ± 1.7 to 0.9 ± 1.3 SDS, P

Original languageEnglish
Pages (from-to)140-144
Number of pages5
JournalEuropean Journal of Endocrinology
Volume141
Issue number2
DOIs
Publication statusPublished - Aug 1999

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Gonadotropin-Releasing Hormone
Statistical Factor Analysis
Puberty
Triptorelin Pamoate
Therapeutics
Retrospective Studies
Central Precocious Puberty

ASJC Scopus subject areas

  • Endocrinology

Cite this

Analysis of the factors affecting auxological response to GnRH agonist treatment and final height outcome in girls with idiopathic central precocious puberty. / Arrigo, Teresa; Cisternino, Mariangela; Galluzzi, Fiorella; Bertelloni, Silvano; Pasquino, Anna Maria; Antoniazzi, Franco; Borrelli, Patrizia; Crisafulli, Giuseppe; Wasniewska, Malgorzata; De Luca, Filippo.

In: European Journal of Endocrinology, Vol. 141, No. 2, 08.1999, p. 140-144.

Research output: Contribution to journalArticle

Arrigo, T, Cisternino, M, Galluzzi, F, Bertelloni, S, Pasquino, AM, Antoniazzi, F, Borrelli, P, Crisafulli, G, Wasniewska, M & De Luca, F 1999, 'Analysis of the factors affecting auxological response to GnRH agonist treatment and final height outcome in girls with idiopathic central precocious puberty', European Journal of Endocrinology, vol. 141, no. 2, pp. 140-144. https://doi.org/10.1530/eje.0.1410140
Arrigo, Teresa ; Cisternino, Mariangela ; Galluzzi, Fiorella ; Bertelloni, Silvano ; Pasquino, Anna Maria ; Antoniazzi, Franco ; Borrelli, Patrizia ; Crisafulli, Giuseppe ; Wasniewska, Malgorzata ; De Luca, Filippo. / Analysis of the factors affecting auxological response to GnRH agonist treatment and final height outcome in girls with idiopathic central precocious puberty. In: European Journal of Endocrinology. 1999 ; Vol. 141, No. 2. pp. 140-144.
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AU - Pasquino, Anna Maria

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