Abstract
The fimA gene coding for the major component (fimbrin) of type 1 fimbriae was mapped within the Salmonella typhi fim gene cluster, and its nucleotide sequence determined. The deduced amino acid sequence of S. typhi fimbrin is highly homologous to that of S. typhimurium type 1 fimbrin and showed similarity to that of other enterobacterial type 1 fimbrins. Downstream of fimA, an open reading frame was found, named fimI, able to encode a fimbrin-like protein. The fimI product could represent the counterpart, in type 1 fimbriae, of the PapH protein involved in cell anchoring and length modulation of Escherichia coli Pap pili. This genetic organization was found to be common to other Salmonella serovars, including S. typhimurium and S. choleraesuis.
| Original language | English |
|---|---|
| Pages (from-to) | 259-265 |
| Number of pages | 7 |
| Journal | FEMS Microbiology Letters |
| Volume | 114 |
| Issue number | 3 |
| Publication status | Published - Dec 15 1993 |
Fingerprint
Keywords
- fim genes
- fimA gene
- fimI gene
- Salmonella typhi
- Type 1 fimbriae
ASJC Scopus subject areas
- Genetics
- Molecular Biology
- Applied Microbiology and Biotechnology
- Microbiology
Cite this
Analysis of the Salmonella fim gene cluster : Identification of a new gene (fimI) encoding a fimbrin-like protein and located downstream from the fimA gene. / Rossolini, Gian Maria; Muscas, Patrizia; Chiesurin, Alessandra; Satta, Giuseppe.
In: FEMS Microbiology Letters, Vol. 114, No. 3, 15.12.1993, p. 259-265.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Analysis of the Salmonella fim gene cluster
T2 - Identification of a new gene (fimI) encoding a fimbrin-like protein and located downstream from the fimA gene
AU - Rossolini, Gian Maria
AU - Muscas, Patrizia
AU - Chiesurin, Alessandra
AU - Satta, Giuseppe
PY - 1993/12/15
Y1 - 1993/12/15
N2 - The fimA gene coding for the major component (fimbrin) of type 1 fimbriae was mapped within the Salmonella typhi fim gene cluster, and its nucleotide sequence determined. The deduced amino acid sequence of S. typhi fimbrin is highly homologous to that of S. typhimurium type 1 fimbrin and showed similarity to that of other enterobacterial type 1 fimbrins. Downstream of fimA, an open reading frame was found, named fimI, able to encode a fimbrin-like protein. The fimI product could represent the counterpart, in type 1 fimbriae, of the PapH protein involved in cell anchoring and length modulation of Escherichia coli Pap pili. This genetic organization was found to be common to other Salmonella serovars, including S. typhimurium and S. choleraesuis.
AB - The fimA gene coding for the major component (fimbrin) of type 1 fimbriae was mapped within the Salmonella typhi fim gene cluster, and its nucleotide sequence determined. The deduced amino acid sequence of S. typhi fimbrin is highly homologous to that of S. typhimurium type 1 fimbrin and showed similarity to that of other enterobacterial type 1 fimbrins. Downstream of fimA, an open reading frame was found, named fimI, able to encode a fimbrin-like protein. The fimI product could represent the counterpart, in type 1 fimbriae, of the PapH protein involved in cell anchoring and length modulation of Escherichia coli Pap pili. This genetic organization was found to be common to other Salmonella serovars, including S. typhimurium and S. choleraesuis.
KW - fim genes
KW - fimA gene
KW - fimI gene
KW - Salmonella typhi
KW - Type 1 fimbriae
UR - http://www.scopus.com/inward/record.url?scp=0027378848&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027378848&partnerID=8YFLogxK
M3 - Article
C2 - 8288102
AN - SCOPUS:0027378848
VL - 114
SP - 259
EP - 265
JO - FEMS Microbiology Letters
JF - FEMS Microbiology Letters
SN - 0378-1097
IS - 3
ER -