Abstract
The present study aimed at reviewing the literature on extraradicular infections of endodontically treated teeth, summarizing the main hypotheses on etiopathogenesis and describing the most suitable techniques to identify the composition of pathogenic extraradicular microorganisms. Medline database was searched using the keywords "Apical biofilm," "extraradicular infection," "secondary endodontic lesion," "endodontic retreatment," "biofilm" either alone or combined with AND. A further hand search was performed on the main endodontic journals. The most frequent bacterial species identified in different studies and with different techniques may vary considerably. Although the presence of some species of microorganisms seems to be determinant, the true origin of extraradicular infection is still undetermined. The literature analysis showed marked differences in methodology, materials, aims, and techniques adopted, which led to highly heterogeneous outcomes. The picture emerging from this review is that extraradicular infection is likely a multifactorial disease that requires further systematic investigation using standardized techniques.
| Original language | English |
|---|---|
| Pages (from-to) | 245-254 |
| Number of pages | 10 |
| Journal | Journal of investigative and clinical dentistry |
| Volume | 5 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Nov 1 2014 |
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Keywords
- extraradicular lesion
- extraradicular microorganisms
- molecular diagnostic techniques
- scanning electron microscopy
- secondary endodontic lesion
ASJC Scopus subject areas
- Medicine(all)
Cite this
Analysis of the secondary endodontic lesions focusing on the extraradicular microorganisms : an overview. / Del Fabbro, Massimo; Samaranayake, Lakshman P.; Lolato, Alessandra; Weinstein, Tommaso; Taschieri, Silvio.
In: Journal of investigative and clinical dentistry, Vol. 5, No. 4, 01.11.2014, p. 245-254.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Analysis of the secondary endodontic lesions focusing on the extraradicular microorganisms
T2 - an overview
AU - Del Fabbro, Massimo
AU - Samaranayake, Lakshman P.
AU - Lolato, Alessandra
AU - Weinstein, Tommaso
AU - Taschieri, Silvio
PY - 2014/11/1
Y1 - 2014/11/1
N2 - The present study aimed at reviewing the literature on extraradicular infections of endodontically treated teeth, summarizing the main hypotheses on etiopathogenesis and describing the most suitable techniques to identify the composition of pathogenic extraradicular microorganisms. Medline database was searched using the keywords "Apical biofilm," "extraradicular infection," "secondary endodontic lesion," "endodontic retreatment," "biofilm" either alone or combined with AND. A further hand search was performed on the main endodontic journals. The most frequent bacterial species identified in different studies and with different techniques may vary considerably. Although the presence of some species of microorganisms seems to be determinant, the true origin of extraradicular infection is still undetermined. The literature analysis showed marked differences in methodology, materials, aims, and techniques adopted, which led to highly heterogeneous outcomes. The picture emerging from this review is that extraradicular infection is likely a multifactorial disease that requires further systematic investigation using standardized techniques.
AB - The present study aimed at reviewing the literature on extraradicular infections of endodontically treated teeth, summarizing the main hypotheses on etiopathogenesis and describing the most suitable techniques to identify the composition of pathogenic extraradicular microorganisms. Medline database was searched using the keywords "Apical biofilm," "extraradicular infection," "secondary endodontic lesion," "endodontic retreatment," "biofilm" either alone or combined with AND. A further hand search was performed on the main endodontic journals. The most frequent bacterial species identified in different studies and with different techniques may vary considerably. Although the presence of some species of microorganisms seems to be determinant, the true origin of extraradicular infection is still undetermined. The literature analysis showed marked differences in methodology, materials, aims, and techniques adopted, which led to highly heterogeneous outcomes. The picture emerging from this review is that extraradicular infection is likely a multifactorial disease that requires further systematic investigation using standardized techniques.
KW - extraradicular lesion
KW - extraradicular microorganisms
KW - molecular diagnostic techniques
KW - scanning electron microscopy
KW - secondary endodontic lesion
UR - http://www.scopus.com/inward/record.url?scp=84940988651&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84940988651&partnerID=8YFLogxK
U2 - 10.1111/jicd.12045
DO - 10.1111/jicd.12045
M3 - Article
C2 - 23766136
AN - SCOPUS:84940988651
VL - 5
SP - 245
EP - 254
JO - Journal of investigative and clinical dentistry
JF - Journal of investigative and clinical dentistry
SN - 2041-1618
IS - 4
ER -