Abstract
Chemotherapy is a major tool for metastatic breast cancer treatment. In this study, a series of 316 patients have been analyzed to evaluate the time needed to reach tumor response by means of combination chemotherapy. Twenty-five percent of patients responded within 3 months and virtually all responses occurred within 7.5 months. The time curves of response (any) and best response are superimposable. A subset analysis has shown that the following pretreatment characteristics predict a significantly longer time to response: prior exposure to adjuvant chemotherapy, nodal positivity at diagnosis, no previous endocrine treatment and osseous metastases.
| Original language | English |
|---|---|
| Pages (from-to) | 460-465 |
| Number of pages | 6 |
| Journal | Oncology |
| Volume | 50 |
| Issue number | 6 |
| Publication status | Published - 1993 |
Keywords
- Advanced breast cancer
- Prognostic factors for response to chemotherapy
- Time to response to chemotherapy
ASJC Scopus subject areas
- Cancer Research
- Oncology