Anaphylaxis in the emergency department: A paediatric perspective

Alberto Martelli, Daniele Ghiglioni, Teresita Sarratud, Elena Calcinai, Suzanne Veehof, Luigi Terracciano, Alessandro Fiocchi

Research output: Contribution to journalArticlepeer-review


PURPOSE OF REVIEW: Correct management of anaphylactic manifestations in the emergency department is crucial to prevent mortality and future episodes, in particular for paediatric patients. We make here recommendations based on a critical review of the evidence for the management of anaphylaxis in emergency department with particular emphasis on children. RECENT FINDINGS: Available information suggests that anaphylaxis must be promptly recognized keeping in mind the airway patency, breathing (ventilation and respiration), circulation and mental status and treated. The first treatment is epinephrine. After successful treatment of an anaphylactic episode, attention must be paid at prevention of early recurrences (biphasic anaphylaxis) and assessment of causes. Patients should not be discharged before prescribing self-injectable epinephrine and explain how and in under what circumstances it must be injected; giving an action plan to be communicated to their communities; inform the school about the possible occurrence of reactions and the appropriate avoidance and rescue measures; and consider the necessity of a Medic-Alert identification. SUMMARY: As gross differences have been described in the awareness of the disease and its management between allergists and nonallergists, allergists should interact with emergency doctors to improve education in this area.

Original languageEnglish
Pages (from-to)321-329
Number of pages9
JournalCurrent Opinion in Allergy and Clinical Immunology
Issue number4
Publication statusPublished - Aug 2008


  • Anaphylaxis
  • Emergency department
  • Epinephrine
  • Food allergy
  • Paediatrics

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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