Anastomotic stenoses occurring after circular stapling in esophageal cancer surgery

G. Petrin, A. Ruol, G. Battaglia, F. Buin, S. Merigliano, M. Constantini, P. Pavei, M. Cagol, S. Scappin, E. Ancona

Research output: Contribution to journalArticlepeer-review


Background: Circular staplers have reduced the incidence of anastomotic leaks in esophagovisceral anastomosis. However, the prevalence of stenosis is greater with staplers than with manual suturing. The aim of this study was to analyze potential risk factors for the onset of anastomotic stenoses and to evaluate their treatment and final outcome. Methods: Between 1990 and 1995, 187 patients underwent esophagectomy and esophagogastrostomy with anastomosis performed inside the chest using a circular stapler. Results: Twenty-three patients (12.3%) developed an anastomotic stenosis. The incidence of strictures was inversely related to the diameter of the stapler. Concomitant cardiovascular diseases; morphofunctional disorders of the tubulized stomach, such as those related to duodenogastric reflux; and neoadjuvant chemotherapy were also recognized as significant risk factors. Endoscopic dilatations proved safe and were effective in the treatment of most anastomotic stenoses. Conclusions: To reduce the risk of anastomotic stenosis after stapled intrathoracic esophagogastrostomy, adequate vascularization of the viscera being anastomized should be maintained, and it is mandatory to use the largest circular stapler suitable. Furthermore, it is essential to reduce the negative inflammation-inducing effects of duodenogastroesophageal reflux to a minimum. Endoscopic dilatations are safe and effective in curing the great majority of anastomotic stenoses.

Original languageEnglish
Pages (from-to)670-674
Number of pages5
JournalSurgical Endoscopy and Other Interventional Techniques
Issue number7
Publication statusPublished - 2000


  • Anastomic stenosis
  • Endoscopic dilatation
  • Esophagogastrostomy
  • Stapled anastomosis

ASJC Scopus subject areas

  • Surgery


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