Abstract
Thirty cases of primary hepatic carcinomas and twenty hepatic metastatic localizations with equivocal histopathological features were investigated using morphologic criteria and immunohistochemical methods. The study was performed on formalin-fixed, paraffin-embedded tissue sections from surgical removed specimens. On the basis of our experience (in according with literature data) we have shown that most of hepatocellular carcinomas express a specific morphologic pattern (i.e. contemporary cholangiocellular differentiation) and phenotypic characters (particularly CEA positivity with bile canalicular pattern). Nevertheless in some cases it is impossible to make a differential diagnosis; the evaluation of new biological parameters like proliferative index will be useful.
Translated title of the contribution | Anatomo-pathologic diagnostic interpretation of nodular hepatic lesions |
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Original language | Italian |
Pages (from-to) | 687-699 |
Number of pages | 13 |
Journal | Pathologica |
Volume | 85 |
Issue number | 1100 |
Publication status | Published - Nov 1993 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine