Abstract
Thirty cases of primary hepatic carcinomas and twenty hepatic metastatic localizations with equivocal histopathological features were investigated using morphologic criteria and immunohistochemical methods. The study was performed on formalin-fixed, paraffin-embedded tissue sections from surgical removed specimens. On the basis of our experience (in according with literature data) we have shown that most of hepatocellular carcinomas express a specific morphologic pattern (i.e. contemporary cholangiocellular differentiation) and phenotypic characters (particularly CEA positivity with bile canalicular pattern). Nevertheless in some cases it is impossible to make a differential diagnosis; the evaluation of new biological parameters like proliferative index will be useful.
| Original language | Italian |
|---|---|
| Pages (from-to) | 687-699 |
| Number of pages | 13 |
| Journal | Pathologica |
| Volume | 85 |
| Issue number | 1100 |
| Publication status | Published - Nov 1993 |
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ASJC Scopus subject areas
- Pathology and Forensic Medicine
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Interpretazione diagnostica anatomo-patologica delle lesioni nodulari epatiche. / Chiaramondia, M.; Ceppa, P.; Baccini, P.; Badini, A.; Castellaneta, A.
In: Pathologica, Vol. 85, No. 1100, 11.1993, p. 687-699.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Interpretazione diagnostica anatomo-patologica delle lesioni nodulari epatiche.
AU - Chiaramondia, M.
AU - Ceppa, P.
AU - Baccini, P.
AU - Badini, A.
AU - Castellaneta, A.
PY - 1993/11
Y1 - 1993/11
N2 - Thirty cases of primary hepatic carcinomas and twenty hepatic metastatic localizations with equivocal histopathological features were investigated using morphologic criteria and immunohistochemical methods. The study was performed on formalin-fixed, paraffin-embedded tissue sections from surgical removed specimens. On the basis of our experience (in according with literature data) we have shown that most of hepatocellular carcinomas express a specific morphologic pattern (i.e. contemporary cholangiocellular differentiation) and phenotypic characters (particularly CEA positivity with bile canalicular pattern). Nevertheless in some cases it is impossible to make a differential diagnosis; the evaluation of new biological parameters like proliferative index will be useful.
AB - Thirty cases of primary hepatic carcinomas and twenty hepatic metastatic localizations with equivocal histopathological features were investigated using morphologic criteria and immunohistochemical methods. The study was performed on formalin-fixed, paraffin-embedded tissue sections from surgical removed specimens. On the basis of our experience (in according with literature data) we have shown that most of hepatocellular carcinomas express a specific morphologic pattern (i.e. contemporary cholangiocellular differentiation) and phenotypic characters (particularly CEA positivity with bile canalicular pattern). Nevertheless in some cases it is impossible to make a differential diagnosis; the evaluation of new biological parameters like proliferative index will be useful.
UR - http://www.scopus.com/inward/record.url?scp=0027693771&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027693771&partnerID=8YFLogxK
M3 - Articolo
C2 - 8170717
AN - SCOPUS:0027693771
VL - 85
SP - 687
EP - 699
JO - Pathologica
JF - Pathologica
SN - 0031-2983
IS - 1100
ER -