Andropausal syndrome in men with systolic heart failure

Michał Tkaczyszyn; Katarzyna Nega; Monika Łopuszańska; Alicja Szklarska; Marek Medraś; Beata Ponikowska; Stephan Von Haehling; Wolfram Doehner; Waldemar Banasiak; Stefan D. Anker; Piotr Ponikowski; Ewa A. Jankowska

Andropausal syndrome in men with systolic heart failure

Michał Tkaczyszyn, Katarzyna Nega, Monika Łopuszańska, Alicja Szklarska, Marek Medraś, Beata Ponikowska, Stephan Von Haehling, Wolfram Doehner, Waldemar Banasiak, Stefan D. Anker, Piotr Ponikowski, Ewa A. Jankowska

Istituto San Raffaele Pisana

Research output: Contribution to journal › Article

Abstract

Introduction Andropausal syndrome (AS) is an element of male aging, being associated with the age-related decline in circulating androgens. Objectives We investigated the prevalence of AS, the severity of andropausal symptoms, and their clinical and hormonal determinants in men with heart failure (HF) and healthy peers. Patients and methods We examined 232 men with systolic HF aged from 40 to 80 years (New York Heart Association [NYHA] class I/II/III-IV: 17%/54%/29%, left ventricular ejection fraction: 30% ±8%) and 362 healthy peers. The severity of 17 andropausal symptoms were assessed using the Aging Males' Symptoms Rating Scale. Results In men with HF aged from 40 to 59 years, the prevalence of AS and the severity of andropausal symptoms were greater than in healthy peers (28% vs. 7%; 40 ±14 vs. 35 ±10 points; both P 0.1). In men with HF aged from 40 to 59 years, advanced NYHA class, low hemoglobin, increased platelet number, and low serum dehydroepiandrosterone sulphate were independently associated with the greater prevalence of AS (all P

Original language	English
Pages (from-to)	156-169
Number of pages	14
Journal	Polskie Archiwum Medycyny Wewnetrznej
Volume	123
Issue number	4
Publication status	Published - 2013

Keywords

Anabolic hormone deficiency
Andropausal syndrome
Heart failure
Male aging
Testosterone

ASJC Scopus subject areas

Internal Medicine

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Andropausal syndrome in men with systolic heart failure. / Tkaczyszyn, Michał; Nega, Katarzyna; Łopuszańska, Monika; Szklarska, Alicja; Medraś, Marek; Ponikowska, Beata; Von Haehling, Stephan; Doehner, Wolfram; Banasiak, Waldemar; Anker, Stefan D.; Ponikowski, Piotr; Jankowska, Ewa A.

In: Polskie Archiwum Medycyny Wewnetrznej, Vol. 123, No. 4, 2013, p. 156-169.

Research output: Contribution to journal › Article

Tkaczyszyn, Michał ; Nega, Katarzyna ; Łopuszańska, Monika ; Szklarska, Alicja ; Medraś, Marek ; Ponikowska, Beata ; Von Haehling, Stephan ; Doehner, Wolfram ; Banasiak, Waldemar ; Anker, Stefan D. ; Ponikowski, Piotr ; Jankowska, Ewa A. / Andropausal syndrome in men with systolic heart failure. In: Polskie Archiwum Medycyny Wewnetrznej. 2013 ; Vol. 123, No. 4. pp. 156-169.

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AU - Tkaczyszyn, Michał

AU - Nega, Katarzyna

AU - Łopuszańska, Monika

AU - Szklarska, Alicja

AU - Medraś, Marek

AU - Ponikowska, Beata

AU - Von Haehling, Stephan

AU - Doehner, Wolfram

AU - Banasiak, Waldemar

AU - Anker, Stefan D.

AU - Ponikowski, Piotr

AU - Jankowska, Ewa A.

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