Anemia in elderly hospitalized patients

prevalence and clinical impact

Margherita Migone De Amicis, Erika Poggiali, Irene Motta, Francesca Minonzio, Giovanna Fabio, Cinzia Hu, Maria Domenica Cappellini

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Anemia is a common finding in elderly individuals. Several studies haveshown a strong relationship between anemia, morbidity and mortality, suggestinganemia as a significant independent predictor of adverse outcome in elderlyhospitalized patients. The pathophisiology of anemia in the elderly is not yet completelyunderstood. Several mechanisms are involved. Weinvestigated the prevalence of anemia in a cohort of 193 elderly patients admitted tothe Internal Medicine Ward of Ca'Granda Policlinico Hospital along 6 months, and itsrelationship to comorbidities and to the length of hospitalization. Anemia was classifiedaccording to the WHO criteria. The majority of patients (48 %) had a mildmoderate,normocytic anemia; severe anemia was found in 8 out of 92 anemicpatients. In a subgroup of patients erythropoietin was tested and resulted statisticallyhigher if compared to non-anemic controls (p = 0.003). Considering the most commoncause of anemia, nutritional deficiency, chronic renal disease and anemia of chronicdisease were found respectively in 36, 15 and 25 % of cases. Unexplained anemiawas diagnosed in 24 % of patients, according to the literature. Anemia wasindependently associated with increased length of hospital stay. Our studyconfirmed a high prevalence of anemia in elderly patients, and its association with ahigher number of comorbidities and a longer stay. A correct clinical approach toanemia in elderly hospitalized patients is essential, considering its negative impact onpatients' quality of life, and its social burden in term of healthcare needs and costs.

Original languageEnglish
Pages (from-to)581-586
Number of pages6
JournalInternal and Emergency Medicine
Volume10
Issue number5
DOIs
Publication statusPublished - Aug 25 2015

Fingerprint

Anemia
Comorbidity
Length of Stay
Internal Medicine
Erythropoietin
Chronic Renal Insufficiency
Malnutrition
Health Care Costs
Hospitalization
Quality of Life
Morbidity
Mortality

Keywords

  • Anemia
  • Elderly
  • Hemoglobin
  • Hospitalization
  • Morbidity
  • Mortality

ASJC Scopus subject areas

  • Emergency Medicine
  • Internal Medicine

Cite this

Anemia in elderly hospitalized patients : prevalence and clinical impact. / Migone De Amicis, Margherita; Poggiali, Erika; Motta, Irene; Minonzio, Francesca; Fabio, Giovanna; Hu, Cinzia; Cappellini, Maria Domenica.

In: Internal and Emergency Medicine, Vol. 10, No. 5, 25.08.2015, p. 581-586.

Research output: Contribution to journalArticle

Migone De Amicis, M, Poggiali, E, Motta, I, Minonzio, F, Fabio, G, Hu, C & Cappellini, MD 2015, 'Anemia in elderly hospitalized patients: prevalence and clinical impact', Internal and Emergency Medicine, vol. 10, no. 5, pp. 581-586. https://doi.org/10.1007/s11739-015-1197-5
Migone De Amicis M, Poggiali E, Motta I, Minonzio F, Fabio G, Hu C et al. Anemia in elderly hospitalized patients: prevalence and clinical impact. Internal and Emergency Medicine. 2015 Aug 25;10(5):581-586. https://doi.org/10.1007/s11739-015-1197-5
Migone De Amicis, Margherita ; Poggiali, Erika ; Motta, Irene ; Minonzio, Francesca ; Fabio, Giovanna ; Hu, Cinzia ; Cappellini, Maria Domenica. / Anemia in elderly hospitalized patients : prevalence and clinical impact. In: Internal and Emergency Medicine. 2015 ; Vol. 10, No. 5. pp. 581-586.
@article{97888b3fedd44f388073ba0c200efa30,
title = "Anemia in elderly hospitalized patients: prevalence and clinical impact",
abstract = "Anemia is a common finding in elderly individuals. Several studies haveshown a strong relationship between anemia, morbidity and mortality, suggestinganemia as a significant independent predictor of adverse outcome in elderlyhospitalized patients. The pathophisiology of anemia in the elderly is not yet completelyunderstood. Several mechanisms are involved. Weinvestigated the prevalence of anemia in a cohort of 193 elderly patients admitted tothe Internal Medicine Ward of Ca'Granda Policlinico Hospital along 6 months, and itsrelationship to comorbidities and to the length of hospitalization. Anemia was classifiedaccording to the WHO criteria. The majority of patients (48 {\%}) had a mildmoderate,normocytic anemia; severe anemia was found in 8 out of 92 anemicpatients. In a subgroup of patients erythropoietin was tested and resulted statisticallyhigher if compared to non-anemic controls (p = 0.003). Considering the most commoncause of anemia, nutritional deficiency, chronic renal disease and anemia of chronicdisease were found respectively in 36, 15 and 25 {\%} of cases. Unexplained anemiawas diagnosed in 24 {\%} of patients, according to the literature. Anemia wasindependently associated with increased length of hospital stay. Our studyconfirmed a high prevalence of anemia in elderly patients, and its association with ahigher number of comorbidities and a longer stay. A correct clinical approach toanemia in elderly hospitalized patients is essential, considering its negative impact onpatients' quality of life, and its social burden in term of healthcare needs and costs.",
keywords = "Anemia, Elderly, Hemoglobin, Hospitalization, Morbidity, Mortality",
author = "{Migone De Amicis}, Margherita and Erika Poggiali and Irene Motta and Francesca Minonzio and Giovanna Fabio and Cinzia Hu and Cappellini, {Maria Domenica}",
year = "2015",
month = "8",
day = "25",
doi = "10.1007/s11739-015-1197-5",
language = "English",
volume = "10",
pages = "581--586",
journal = "Internal and Emergency Medicine",
issn = "1828-0447",
publisher = "Springer-Verlag Italia s.r.l.",
number = "5",

}

TY - JOUR

T1 - Anemia in elderly hospitalized patients

T2 - prevalence and clinical impact

AU - Migone De Amicis, Margherita

AU - Poggiali, Erika

AU - Motta, Irene

AU - Minonzio, Francesca

AU - Fabio, Giovanna

AU - Hu, Cinzia

AU - Cappellini, Maria Domenica

PY - 2015/8/25

Y1 - 2015/8/25

N2 - Anemia is a common finding in elderly individuals. Several studies haveshown a strong relationship between anemia, morbidity and mortality, suggestinganemia as a significant independent predictor of adverse outcome in elderlyhospitalized patients. The pathophisiology of anemia in the elderly is not yet completelyunderstood. Several mechanisms are involved. Weinvestigated the prevalence of anemia in a cohort of 193 elderly patients admitted tothe Internal Medicine Ward of Ca'Granda Policlinico Hospital along 6 months, and itsrelationship to comorbidities and to the length of hospitalization. Anemia was classifiedaccording to the WHO criteria. The majority of patients (48 %) had a mildmoderate,normocytic anemia; severe anemia was found in 8 out of 92 anemicpatients. In a subgroup of patients erythropoietin was tested and resulted statisticallyhigher if compared to non-anemic controls (p = 0.003). Considering the most commoncause of anemia, nutritional deficiency, chronic renal disease and anemia of chronicdisease were found respectively in 36, 15 and 25 % of cases. Unexplained anemiawas diagnosed in 24 % of patients, according to the literature. Anemia wasindependently associated with increased length of hospital stay. Our studyconfirmed a high prevalence of anemia in elderly patients, and its association with ahigher number of comorbidities and a longer stay. A correct clinical approach toanemia in elderly hospitalized patients is essential, considering its negative impact onpatients' quality of life, and its social burden in term of healthcare needs and costs.

AB - Anemia is a common finding in elderly individuals. Several studies haveshown a strong relationship between anemia, morbidity and mortality, suggestinganemia as a significant independent predictor of adverse outcome in elderlyhospitalized patients. The pathophisiology of anemia in the elderly is not yet completelyunderstood. Several mechanisms are involved. Weinvestigated the prevalence of anemia in a cohort of 193 elderly patients admitted tothe Internal Medicine Ward of Ca'Granda Policlinico Hospital along 6 months, and itsrelationship to comorbidities and to the length of hospitalization. Anemia was classifiedaccording to the WHO criteria. The majority of patients (48 %) had a mildmoderate,normocytic anemia; severe anemia was found in 8 out of 92 anemicpatients. In a subgroup of patients erythropoietin was tested and resulted statisticallyhigher if compared to non-anemic controls (p = 0.003). Considering the most commoncause of anemia, nutritional deficiency, chronic renal disease and anemia of chronicdisease were found respectively in 36, 15 and 25 % of cases. Unexplained anemiawas diagnosed in 24 % of patients, according to the literature. Anemia wasindependently associated with increased length of hospital stay. Our studyconfirmed a high prevalence of anemia in elderly patients, and its association with ahigher number of comorbidities and a longer stay. A correct clinical approach toanemia in elderly hospitalized patients is essential, considering its negative impact onpatients' quality of life, and its social burden in term of healthcare needs and costs.

KW - Anemia

KW - Elderly

KW - Hemoglobin

KW - Hospitalization

KW - Morbidity

KW - Mortality

UR - http://www.scopus.com/inward/record.url?scp=84937966835&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84937966835&partnerID=8YFLogxK

U2 - 10.1007/s11739-015-1197-5

DO - 10.1007/s11739-015-1197-5

M3 - Article

VL - 10

SP - 581

EP - 586

JO - Internal and Emergency Medicine

JF - Internal and Emergency Medicine

SN - 1828-0447

IS - 5

ER -