Anetodermic lupus panniculitis and antiphospholipid antibodies

Report of three cases

Angelo V. Marzano, Miriam Vanotti, Elvio Alessi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Anetoderma is a rare cutaneous disease characterized by a loss of normal elastic tissue that is presented clinically as localized areas of wrinkled or flaccid skin. This form may be associated with several immunological abnormalities, most notably lupus erythematosus and antiphospholipid antibodies with or without clinical manifestations of the antiphospholipid syndrome. A retrospective study was conducted with the aim of summarizing the clinical characteristics, course and laboratory findings in three women with anetoderma-associated lupus erythematosus panniculitis, an unusual variant of cutaneous lupus erythematosus. The 3 patients (of the 12 patients with lupus erythematosus panniculitis seen by us since 1990) were all at a young age at onset of panniculitis (median, 22 years). None of the patients developed severe systemic involvement up to 9 years (median, 5 years) from onset of the disease. The most noteworthy laboratory finding was the presence of antiphospholipid antibodies. Anetodermic lupus erythematosus panniculitis may be regarded as an uncommon variant of cutaneous lupus erythematosus mainly affecting young females and showing a favourable clinical course, although the patients should be followed and screened for the emergence of antiphospholipid syndrome. Antiphospholipid antibodies could play a role in the elastolytic process, leading to anetoderma.

Original languageEnglish
Pages (from-to)385-388
Number of pages4
JournalActa Dermato-Venereologica
Volume84
Issue number5
DOIs
Publication statusPublished - 2004

Fingerprint

Lupus Erythematosus Panniculitis
Anetoderma
Antiphospholipid Antibodies
Cutaneous Lupus Erythematosus
Disease
Antiphospholipid Syndrome
Panniculitis
Elastic Tissue
Rare Diseases
Age of Onset
Skin Diseases
Retrospective Studies
Skin

Keywords

  • Anetoderma
  • Antiphospholipid antibodies
  • Lupus erythematosus
  • Panniculitis

ASJC Scopus subject areas

  • Dermatology

Cite this

Anetodermic lupus panniculitis and antiphospholipid antibodies : Report of three cases. / Marzano, Angelo V.; Vanotti, Miriam; Alessi, Elvio.

In: Acta Dermato-Venereologica, Vol. 84, No. 5, 2004, p. 385-388.

Research output: Contribution to journalArticle

@article{2287503f2e224e6fa5e4dc3d605c829d,
title = "Anetodermic lupus panniculitis and antiphospholipid antibodies: Report of three cases",
abstract = "Anetoderma is a rare cutaneous disease characterized by a loss of normal elastic tissue that is presented clinically as localized areas of wrinkled or flaccid skin. This form may be associated with several immunological abnormalities, most notably lupus erythematosus and antiphospholipid antibodies with or without clinical manifestations of the antiphospholipid syndrome. A retrospective study was conducted with the aim of summarizing the clinical characteristics, course and laboratory findings in three women with anetoderma-associated lupus erythematosus panniculitis, an unusual variant of cutaneous lupus erythematosus. The 3 patients (of the 12 patients with lupus erythematosus panniculitis seen by us since 1990) were all at a young age at onset of panniculitis (median, 22 years). None of the patients developed severe systemic involvement up to 9 years (median, 5 years) from onset of the disease. The most noteworthy laboratory finding was the presence of antiphospholipid antibodies. Anetodermic lupus erythematosus panniculitis may be regarded as an uncommon variant of cutaneous lupus erythematosus mainly affecting young females and showing a favourable clinical course, although the patients should be followed and screened for the emergence of antiphospholipid syndrome. Antiphospholipid antibodies could play a role in the elastolytic process, leading to anetoderma.",
keywords = "Anetoderma, Antiphospholipid antibodies, Lupus erythematosus, Panniculitis",
author = "Marzano, {Angelo V.} and Miriam Vanotti and Elvio Alessi",
year = "2004",
doi = "10.1080/00015550410030691",
language = "English",
volume = "84",
pages = "385--388",
journal = "Acta Borealia",
issn = "0001-5555",
publisher = "Society for the Publication of Acta Dermato-Venereologica",
number = "5",

}

TY - JOUR

T1 - Anetodermic lupus panniculitis and antiphospholipid antibodies

T2 - Report of three cases

AU - Marzano, Angelo V.

AU - Vanotti, Miriam

AU - Alessi, Elvio

PY - 2004

Y1 - 2004

N2 - Anetoderma is a rare cutaneous disease characterized by a loss of normal elastic tissue that is presented clinically as localized areas of wrinkled or flaccid skin. This form may be associated with several immunological abnormalities, most notably lupus erythematosus and antiphospholipid antibodies with or without clinical manifestations of the antiphospholipid syndrome. A retrospective study was conducted with the aim of summarizing the clinical characteristics, course and laboratory findings in three women with anetoderma-associated lupus erythematosus panniculitis, an unusual variant of cutaneous lupus erythematosus. The 3 patients (of the 12 patients with lupus erythematosus panniculitis seen by us since 1990) were all at a young age at onset of panniculitis (median, 22 years). None of the patients developed severe systemic involvement up to 9 years (median, 5 years) from onset of the disease. The most noteworthy laboratory finding was the presence of antiphospholipid antibodies. Anetodermic lupus erythematosus panniculitis may be regarded as an uncommon variant of cutaneous lupus erythematosus mainly affecting young females and showing a favourable clinical course, although the patients should be followed and screened for the emergence of antiphospholipid syndrome. Antiphospholipid antibodies could play a role in the elastolytic process, leading to anetoderma.

AB - Anetoderma is a rare cutaneous disease characterized by a loss of normal elastic tissue that is presented clinically as localized areas of wrinkled or flaccid skin. This form may be associated with several immunological abnormalities, most notably lupus erythematosus and antiphospholipid antibodies with or without clinical manifestations of the antiphospholipid syndrome. A retrospective study was conducted with the aim of summarizing the clinical characteristics, course and laboratory findings in three women with anetoderma-associated lupus erythematosus panniculitis, an unusual variant of cutaneous lupus erythematosus. The 3 patients (of the 12 patients with lupus erythematosus panniculitis seen by us since 1990) were all at a young age at onset of panniculitis (median, 22 years). None of the patients developed severe systemic involvement up to 9 years (median, 5 years) from onset of the disease. The most noteworthy laboratory finding was the presence of antiphospholipid antibodies. Anetodermic lupus erythematosus panniculitis may be regarded as an uncommon variant of cutaneous lupus erythematosus mainly affecting young females and showing a favourable clinical course, although the patients should be followed and screened for the emergence of antiphospholipid syndrome. Antiphospholipid antibodies could play a role in the elastolytic process, leading to anetoderma.

KW - Anetoderma

KW - Antiphospholipid antibodies

KW - Lupus erythematosus

KW - Panniculitis

UR - http://www.scopus.com/inward/record.url?scp=4744369181&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4744369181&partnerID=8YFLogxK

U2 - 10.1080/00015550410030691

DO - 10.1080/00015550410030691

M3 - Article

VL - 84

SP - 385

EP - 388

JO - Acta Borealia

JF - Acta Borealia

SN - 0001-5555

IS - 5

ER -