Aneurysmal bone cyst and giant cell tumor of the foot

Roberto Casadei, Pietro Ruggieri, Manuela Moscato, Andrea Ferraro, Piero Picci

Research output: Contribution to journalArticle

Abstract

From 1950 to 1994, 257 cases of benign bone tumors of the foot were treated at the Bone Tumor Center of the Rizzoli Institute. Aneurysmal bone cysts (ABC) and giant cell tumors (GCT) are rare and often they are misdiagnosed. To define the clinical and radiographic features useful for diagnosis, x-rays of 24 ABCs and 21 GCTs of the foot were reviewed. Adding our series to the cases reported in the literature, the only important clinical data that emerged was the average age of patients affected by ABC and GCT (15 and 27 years, respectively). ABCs localized in small tarsal bones were rare (6%), whereas 19% of GCTs were found in this site. The eccentric, round shape of a lytic lesion was more characteristic of GCT. An aggressive pattern of radiographic bone destruction was observed more frequently in GCT than in ABC (P = 0.01). Septation was seen in both tumors. Typical of ABC was a sharp and trabeculated margin, whereas GCT had an ill-defined edge with normal cancellous bone (P = 0.007). The growth of ABCs often expanded the cortex, while GCTs eroded, thinned, and broke the cortical bone (P = 0.001). A saucerized cortex was observed only in ABCs. A bone shell was more characteristic of ABC than of GCT (P = 0.002). Pathologic fractures (67%) and joint involvement, evaluated by computed tomography and magnetic resonance imaging (83%), were more frequent in GCTs, whereas fluid levels were more frequently observed in ABCs (47%). The majority of the tumors were stage 2, but GCTs represented 70% of stage 3 aggressive lesions.

Original languageEnglish
Pages (from-to)487-495
Number of pages9
JournalFoot and Ankle International
Volume17
Issue number8
Publication statusPublished - Aug 1996

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Aneurysmal Bone Cysts
Giant Cell Tumors
Foot
Bone and Bones
Neoplasms
Foot Bones
Tarsal Bones
Spontaneous Fractures
Bone Fractures
Diagnostic Errors
Joints
Tomography
Magnetic Resonance Imaging
X-Rays
Growth

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Casadei, R., Ruggieri, P., Moscato, M., Ferraro, A., & Picci, P. (1996). Aneurysmal bone cyst and giant cell tumor of the foot. Foot and Ankle International, 17(8), 487-495.

Aneurysmal bone cyst and giant cell tumor of the foot. / Casadei, Roberto; Ruggieri, Pietro; Moscato, Manuela; Ferraro, Andrea; Picci, Piero.

In: Foot and Ankle International, Vol. 17, No. 8, 08.1996, p. 487-495.

Research output: Contribution to journalArticle

Casadei, R, Ruggieri, P, Moscato, M, Ferraro, A & Picci, P 1996, 'Aneurysmal bone cyst and giant cell tumor of the foot', Foot and Ankle International, vol. 17, no. 8, pp. 487-495.
Casadei R, Ruggieri P, Moscato M, Ferraro A, Picci P. Aneurysmal bone cyst and giant cell tumor of the foot. Foot and Ankle International. 1996 Aug;17(8):487-495.
Casadei, Roberto ; Ruggieri, Pietro ; Moscato, Manuela ; Ferraro, Andrea ; Picci, Piero. / Aneurysmal bone cyst and giant cell tumor of the foot. In: Foot and Ankle International. 1996 ; Vol. 17, No. 8. pp. 487-495.
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