Aneurysmal bone cyst does not hinder the success of kidney transplantation. A case report

Mario Giordano, Giorgia Caloro, Alberto Gaeta, Antonio Vergori, Luisa Santangelo, Paolo Giordano, Pietro Ruggieri

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Abstract

Uremic osteodystrophy is an expected complication in subjects with chronic renal insufficiency. It develops gradually and progressively already during the conservative treatment and then during the dialysis treatment. It can present a wide histopathological spectrum including typical alterations (from osteitis fibrosa to osteomalacia and/or mixed lesions) or, more rarely, isolated bone lesions indicative of a brown tumor of the bone. These conditions must be clearly identified in the pretransplant phase, especially if a bone lesion indicative of a pathological condition possibly evolving into a neoplasm is detected fortuitously. We report the case of a 19-yr-old boy with renal insufficiency and candidate for a pre-emptive renal transplantation from a living donor, in whom the diagnosis of ABC of the pubic symphysis - asymptomatic and fortuitously detected while performing instrumental investigations - was suspected through the imaging studies (CT scan, MRI) and was confirmed by the histological examination. This made it possible to perform the renal transplant. The immunosuppressive treatment, which was subsequently administered, was based on steroids, calcineurin inhibitors (tacrolimus), and mycophenolate and did not determine any modification in the radiological aspect of the bone lesion, even after more than one yr from the transplant.

Original languageEnglish
Pages (from-to)E33-E36
JournalPediatric Transplantation
Volume19
Issue number2
DOIs
Publication statusPublished - Mar 1 2015

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Keywords

  • immunosuppressive treatment
  • kidney transplant
  • uremic osteodystrophy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation
  • Medicine(all)

Cite this

Giordano, M., Caloro, G., Gaeta, A., Vergori, A., Santangelo, L., Giordano, P., & Ruggieri, P. (2015). Aneurysmal bone cyst does not hinder the success of kidney transplantation. A case report. Pediatric Transplantation, 19(2), E33-E36. https://doi.org/10.1111/petr.12414