Angiogenesis in atherogenesis

Joerg Herrmann, Lilach O. Lerman, Debabrata Mukhopadhyay, Claudio Napoli, Amir Lerman

Research output: Contribution to journalArticlepeer-review

Abstract

Atherogenesis is the pathobiological process, which underlies atherosclerotic cardiovascular disease and evolves in the 3 stages of initiation, progression, and complication to clinical significance. Of note, this process is associated with neovascularization, and it was not until recently that the implications of angiogenesis in atherogenesis were delineated. This article gives an updated overview on this topic and briefly reflects on the similarities with neovessel formation in carcinogenesis.

Original languageEnglish
Pages (from-to)1948-1957
Number of pages10
JournalArteriosclerosis, Thrombosis, and Vascular Biology
Volume26
Issue number9
DOIs
Publication statusPublished - Sep 2006

Keywords

  • Atherosclerosis
  • Cancer
  • Neovascularization
  • Oxidative stress
  • Pathology

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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