Angiographic Analysis of Pattern of Late Luminal Loss in Sirolimus- and Paclitaxel-Eluting Stents

Pierfrancesco Agostoni, John Cosgrave, Giuseppe G L Biondi-Zoccai, Giuseppe M. Sangiorgi, Lei Ge, Gloria Melzi, Simon Corbett, Flavio Airoldi, Matteo Montorfano, Alaide Chieffo, Iassen Michev, Mauro Carlino, Antonio Colombo

Research output: Contribution to journalArticlepeer-review


Late loss is becoming an important end point to compare drug-eluting stents; however, little is known about its pattern of distribution. We analyzed the pattern of late loss distribution in sirolimus-eluting stents (SESs) and paclitaxel-eluting stents (PESs) in a consecutive cohort of patients. From a cohort of 529 patients treated with drug-eluting stents in 1 year, we selected all patients who underwent angiographic follow-up. Three hundred fifty-nine patients with 592 de novo lesions received SESs (286 lesions) or PESs (306 lesions). Late loss and binary angiographic restenosis were analyzed. Binary restenosis occurred in 56 lesions (19.6%) treated with SESs compared with 53 (17.3%) treated with PESs (p = 0.48). The 2 late loss distributions were skewed to the right and were not normally distributed (p

Original languageEnglish
Pages (from-to)593-598
Number of pages6
JournalThe American Journal of Cardiology
Issue number5
Publication statusPublished - Mar 1 2007

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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