Abstract
Angiosarcoma of the breast is one of the rarest malignancies. Breast angiosarcoma can be classified into primary when arising de novo and secondary to chronic lymphoedema or breast irradiation. Molecular pathways involved in angiosarcoma development have not been described dearly, yet some gene point mutations and protein altered expression levels have been detected. So far, their management is based above all on surgery. Hence, further studies starting from the few known key points may help to develop more effective strategies based lx)th on target therapies, together with surgery.
Original language | English |
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Pages (from-to) | S510-S517 |
Journal | Translational Cancer Research |
Volume | 8 |
Issue number | 5 |
DOIs | |
Publication status | Published - Oct 1 2019 |
Keywords
- Angiosarcoma
- breast
- mesenchymal tumours