Angioseal use after antegrade femoral arteriotomy in patients undergoing percutaneous revascularization for critical limb ischemia: A case series

Giuseppe G L Biondi-Zoccai, Massimiliano Fusaro, Abdulkafi Tashani, Nadia Mollichelli, Massimo Medda, Graziella De Giacobbi, Luigi Inglese

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Antegrade femoral artery access is commonly used for percutaneous transluminal revascularization of ipsilateral lower limbs in patients with critical limb ischemia. While hemostasis at the end of the procedure can be achieved by manual compression, this may lead to an increase in local vascular complications. Femoral artery closure devices, such as the Angioseal collagen plug and anchor device, have been approved and shown of benefit after retrograde femoral artery catheterization. To date, there are however no data on the use of such arteriotomy closure device after antegrade femoral access. We hereby report a case series of five patients in whom Angioseal was successfully used after antegrade femoral puncture and below-the-knee percutaneous transluminal angioplasty. In all cases the device enabled immediate and complete hemostasis without major complications, despite the intense antithrombotic regimen, including heparin, aspirin, and clopidogrel in all patients, as well as glycoprotein IIb/IIIa inhibitors (in two patients) and fibrinolytic therapy (in one).

Original languageEnglish
Pages (from-to)398-399
Number of pages2
JournalInternational Journal of Cardiology
Volume118
Issue number3
DOIs
Publication statusPublished - Jun 12 2007

Fingerprint

Thigh
Femoral Artery
Ischemia
Extremities
Equipment and Supplies
clopidogrel
Hemostasis
Platelet Glycoprotein GPIIb-IIIa Complex
Thrombolytic Therapy
Angioplasty
Punctures
Catheterization
Aspirin
Blood Vessels
Heparin
Lower Extremity
Knee
Collagen

Keywords

  • Arterial closure device
  • Case series
  • Critical limb ischemia
  • Peripheral artery disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Angioseal use after antegrade femoral arteriotomy in patients undergoing percutaneous revascularization for critical limb ischemia : A case series. / Biondi-Zoccai, Giuseppe G L; Fusaro, Massimiliano; Tashani, Abdulkafi; Mollichelli, Nadia; Medda, Massimo; De Giacobbi, Graziella; Inglese, Luigi.

In: International Journal of Cardiology, Vol. 118, No. 3, 12.06.2007, p. 398-399.

Research output: Contribution to journalArticle

Biondi-Zoccai, Giuseppe G L ; Fusaro, Massimiliano ; Tashani, Abdulkafi ; Mollichelli, Nadia ; Medda, Massimo ; De Giacobbi, Graziella ; Inglese, Luigi. / Angioseal use after antegrade femoral arteriotomy in patients undergoing percutaneous revascularization for critical limb ischemia : A case series. In: International Journal of Cardiology. 2007 ; Vol. 118, No. 3. pp. 398-399.
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