The identification of disease etiopathogenetic mechanisms and the development of new therapeutic strategies are often the result of the possibility of reproducing human clinical conditions in laboratiry animal models. The anatomical, functional and/or organic alterations can be induced by drugs or surgery, or they can be already present in repeatedly crossbred animals manifesting them more frequently. Modern biothechnologies also make it possible to obtain transgenic models. The time factor represents another advantage of experimentation on animal models. In fact, disease onset and evolution, as well as therapeutic effects, occur more rapidly in animals with a shorter average life with respect to humans.
|Translated title of the contribution||Animal models in pediatric surgery|
|Number of pages||25|
|Publication status||Published - 2000|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health