Anodal tDCS during face-name associations memory training in Alzheimer's patients

Maria Cotelli, Rosa Manenti, Michela Petesi, Michela Brambilla, Sandra Rosini, Clarissa Ferrari, Orazio Zanetti, Carlo Miniussi

Research output: Contribution to journalArticle

Abstract

Objective: Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer's disease (AD) have gained attention in recent years. The aim of the present study is to investigate the effects of anodal tDCS (AtDCS) combined with memory training on face-name associations in an AD patient sample. Methods: Thirty six AD patients were randomly assigned to one of three study groups: Group 1, AtDCS plus individualized computerized memory training; Group 2, placebo tDCS plus individualized computerized memory training; Group 3, AtDCS plus motor training. Results: A general improvement in performance was observed after 2 weeks of memory training. Both the anodal tDCS plus individualized computerized memory training and the placebo tDCS plus individualized computerized memory training groups had significantly improved performances at 2 weeks compared with the AtDCS plus motor training group. Conclusion: Our findings suggest a beneficial effect of individualized memory rehabilitation in AD patients.

Original languageEnglish
Article numberArticle 38
JournalFrontiers in Aging Neuroscience
Volume6
Issue numberMAR
DOIs
Publication statusPublished - 2014

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Keywords

  • Dementia
  • Memory
  • Stimulation
  • Tdcs
  • Training

ASJC Scopus subject areas

  • Ageing
  • Cognitive Neuroscience

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