Anodal tDCS during face-name associations memory training in Alzheimer's patients

Maria Cotelli, Rosa Manenti, Michela Petesi, Michela Brambilla, Sandra Rosini, Clarissa Ferrari, Orazio Zanetti, Carlo Miniussi

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Objective: Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer's disease (AD) have gained attention in recent years. The aim of the present study is to investigate the effects of anodal tDCS (AtDCS) combined with memory training on face-name associations in an AD patient sample. Methods: Thirty six AD patients were randomly assigned to one of three study groups: Group 1, AtDCS plus individualized computerized memory training; Group 2, placebo tDCS plus individualized computerized memory training; Group 3, AtDCS plus motor training. Results: A general improvement in performance was observed after 2 weeks of memory training. Both the anodal tDCS plus individualized computerized memory training and the placebo tDCS plus individualized computerized memory training groups had significantly improved performances at 2 weeks compared with the AtDCS plus motor training group. Conclusion: Our findings suggest a beneficial effect of individualized memory rehabilitation in AD patients.

Original languageEnglish
Article numberArticle 38
JournalFrontiers in Aging Neuroscience
Volume6
Issue numberMAR
DOIs
Publication statusPublished - 2014

Fingerprint

Names
Learning
Alzheimer Disease
Placebos
Transcranial Direct Current Stimulation
Rehabilitation
Pharmacology

Keywords

  • Dementia
  • Memory
  • Stimulation
  • Tdcs
  • Training

ASJC Scopus subject areas

  • Ageing
  • Cognitive Neuroscience

Cite this

Anodal tDCS during face-name associations memory training in Alzheimer's patients. / Cotelli, Maria; Manenti, Rosa; Petesi, Michela; Brambilla, Michela; Rosini, Sandra; Ferrari, Clarissa; Zanetti, Orazio; Miniussi, Carlo.

In: Frontiers in Aging Neuroscience, Vol. 6, No. MAR, Article 38, 2014.

Research output: Contribution to journalArticle

@article{687bdbbfa0a74a18833a635db957b041,
title = "Anodal tDCS during face-name associations memory training in Alzheimer's patients",
abstract = "Objective: Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer's disease (AD) have gained attention in recent years. The aim of the present study is to investigate the effects of anodal tDCS (AtDCS) combined with memory training on face-name associations in an AD patient sample. Methods: Thirty six AD patients were randomly assigned to one of three study groups: Group 1, AtDCS plus individualized computerized memory training; Group 2, placebo tDCS plus individualized computerized memory training; Group 3, AtDCS plus motor training. Results: A general improvement in performance was observed after 2 weeks of memory training. Both the anodal tDCS plus individualized computerized memory training and the placebo tDCS plus individualized computerized memory training groups had significantly improved performances at 2 weeks compared with the AtDCS plus motor training group. Conclusion: Our findings suggest a beneficial effect of individualized memory rehabilitation in AD patients.",
keywords = "Dementia, Memory, Stimulation, Tdcs, Training",
author = "Maria Cotelli and Rosa Manenti and Michela Petesi and Michela Brambilla and Sandra Rosini and Clarissa Ferrari and Orazio Zanetti and Carlo Miniussi",
year = "2014",
doi = "10.3389/fnagi.2014.00038",
language = "English",
volume = "6",
journal = "Frontiers in Aging Neuroscience",
issn = "1663-4365",
publisher = "Frontiers Research Foundation",
number = "MAR",

}

TY - JOUR

T1 - Anodal tDCS during face-name associations memory training in Alzheimer's patients

AU - Cotelli, Maria

AU - Manenti, Rosa

AU - Petesi, Michela

AU - Brambilla, Michela

AU - Rosini, Sandra

AU - Ferrari, Clarissa

AU - Zanetti, Orazio

AU - Miniussi, Carlo

PY - 2014

Y1 - 2014

N2 - Objective: Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer's disease (AD) have gained attention in recent years. The aim of the present study is to investigate the effects of anodal tDCS (AtDCS) combined with memory training on face-name associations in an AD patient sample. Methods: Thirty six AD patients were randomly assigned to one of three study groups: Group 1, AtDCS plus individualized computerized memory training; Group 2, placebo tDCS plus individualized computerized memory training; Group 3, AtDCS plus motor training. Results: A general improvement in performance was observed after 2 weeks of memory training. Both the anodal tDCS plus individualized computerized memory training and the placebo tDCS plus individualized computerized memory training groups had significantly improved performances at 2 weeks compared with the AtDCS plus motor training group. Conclusion: Our findings suggest a beneficial effect of individualized memory rehabilitation in AD patients.

AB - Objective: Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer's disease (AD) have gained attention in recent years. The aim of the present study is to investigate the effects of anodal tDCS (AtDCS) combined with memory training on face-name associations in an AD patient sample. Methods: Thirty six AD patients were randomly assigned to one of three study groups: Group 1, AtDCS plus individualized computerized memory training; Group 2, placebo tDCS plus individualized computerized memory training; Group 3, AtDCS plus motor training. Results: A general improvement in performance was observed after 2 weeks of memory training. Both the anodal tDCS plus individualized computerized memory training and the placebo tDCS plus individualized computerized memory training groups had significantly improved performances at 2 weeks compared with the AtDCS plus motor training group. Conclusion: Our findings suggest a beneficial effect of individualized memory rehabilitation in AD patients.

KW - Dementia

KW - Memory

KW - Stimulation

KW - Tdcs

KW - Training

UR - http://www.scopus.com/inward/record.url?scp=84898042302&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84898042302&partnerID=8YFLogxK

U2 - 10.3389/fnagi.2014.00038

DO - 10.3389/fnagi.2014.00038

M3 - Article

VL - 6

JO - Frontiers in Aging Neuroscience

JF - Frontiers in Aging Neuroscience

SN - 1663-4365

IS - MAR

M1 - Article 38

ER -