TY - JOUR
T1 - Anorgasmia during pregabalin add-on therapy for partial seizures
AU - Calabrò, Rocco Salvatore
AU - De Luca, Rosaria
AU - Pollicino, Patrizia
AU - Bramanti, Placido
PY - 2013/9
Y1 - 2013/9
N2 - Anorgasmia is the inability to reach orgasm during sexual intercourse, and, although it is believed that around 90% of anorgasmia problems are related to psychological issues, the use of serotoninergic drugs, including antidepressants and atypical antipsychotics, is a common cause of situational anorgasmia. Pregabalin is a new antiepileptic drug, structurally related to gabapentin, and commonly used as adjunctive therapy for partial epilepsy and treatment of neuropathic pain in adults. Herein, we describe three men with epilepsy, who experienced severe anorgasmia after pregabalin add-on treatment.
AB - Anorgasmia is the inability to reach orgasm during sexual intercourse, and, although it is believed that around 90% of anorgasmia problems are related to psychological issues, the use of serotoninergic drugs, including antidepressants and atypical antipsychotics, is a common cause of situational anorgasmia. Pregabalin is a new antiepileptic drug, structurally related to gabapentin, and commonly used as adjunctive therapy for partial epilepsy and treatment of neuropathic pain in adults. Herein, we describe three men with epilepsy, who experienced severe anorgasmia after pregabalin add-on treatment.
KW - Anorgasmia
KW - Pregabalin
KW - Sexual dysfunction
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U2 - 10.1684/epd.2013.0592
DO - 10.1684/epd.2013.0592
M3 - Article
C2 - 23906723
AN - SCOPUS:84884694716
VL - 15
SP - 358
EP - 361
JO - Epileptic Disorders
JF - Epileptic Disorders
SN - 1294-9361
IS - 3
ER -