Antenatal manifestation of congenital pancreatoblastoma in a fetus with Beckwith-Wiedemann syndrome

Gloria Pelizzo, Giancarlo Conoscenti, Karim D. Kalache, Francesco Vesce, Paolo Guerrini, Luigi Cavazzini

Research output: Contribution to journal › Article

Abstract

Antenatal detection of an isolated abdominal cyst was found to be a pancreatoblastoma in a female fetus with Beckwith-Wiedemann syndrome. Prenatal and post-natal features and management of this very rare tumour are discussed. Molecular investigation disclosed a mosaic paternal 11p15 uniparental disomy in the tumoral cells. The prognosis of a congenital pancreatoblastoma is good if complete surgical excision is achieved. However, the association with Beckwith-Wiedemann syndrome requires a prolonged follow-up because of the increased risk of developing malignant tumours.

Original languageEnglish
Pages (from-to)292-294
Number of pages3
JournalPrenatal Diagnosis
Volume23
Issue number4
DOIs
Publication statusPublished - Apr 1 2003

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Beckwith-Wiedemann Syndrome
Fetus
Uniparental Disomy
Cysts
Neoplasms
Pancreatoblastoma

Keywords

  • Beckwith-Wiedemann syndrome
  • Pancreatoblastoma
  • Prenatal diagnosis
  • Ultrasonography
  • Uniparental disomy

ASJC Scopus subject areas

  • Genetics(clinical)
  • Obstetrics and Gynaecology

Cite this

Pelizzo, G., Conoscenti, G., Kalache, K. D., Vesce, F., Guerrini, P., & Cavazzini, L. (2003). Antenatal manifestation of congenital pancreatoblastoma in a fetus with Beckwith-Wiedemann syndrome. Prenatal Diagnosis, 23(4), 292-294. https://doi.org/10.1002/pd.575

Antenatal manifestation of congenital pancreatoblastoma in a fetus with Beckwith-Wiedemann syndrome. / Pelizzo, Gloria; Conoscenti, Giancarlo; Kalache, Karim D.; Vesce, Francesco; Guerrini, Paolo; Cavazzini, Luigi.

In: Prenatal Diagnosis, Vol. 23, No. 4, 01.04.2003, p. 292-294.

Research output: Contribution to journal › Article

Pelizzo, G, Conoscenti, G, Kalache, KD, Vesce, F, Guerrini, P & Cavazzini, L 2003, 'Antenatal manifestation of congenital pancreatoblastoma in a fetus with Beckwith-Wiedemann syndrome', Prenatal Diagnosis, vol. 23, no. 4, pp. 292-294. https://doi.org/10.1002/pd.575
Pelizzo G, Conoscenti G, Kalache KD, Vesce F, Guerrini P, Cavazzini L. Antenatal manifestation of congenital pancreatoblastoma in a fetus with Beckwith-Wiedemann syndrome. Prenatal Diagnosis. 2003 Apr 1;23(4):292-294. https://doi.org/10.1002/pd.575
Pelizzo, Gloria ; Conoscenti, Giancarlo ; Kalache, Karim D. ; Vesce, Francesco ; Guerrini, Paolo ; Cavazzini, Luigi. / Antenatal manifestation of congenital pancreatoblastoma in a fetus with Beckwith-Wiedemann syndrome. In: Prenatal Diagnosis. 2003 ; Vol. 23, No. 4. pp. 292-294.
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