Abstract
During 1984-88 a population-based case-control study was carried out in The Netherlands, in collaboration with the International Agency for Research on Cancer, to examine the possible relationship between aspects of medical history and exocrine pancreatic carcinoma in 176 cases and 487 controls. About 58% of patients were interviewed directly. In women, a significant, positive dose-response effect of height was seen (p-value trend <0.005). Compared with ages 14 or more, women with an early age at menarche, i.e., 11 years or less, had a 3-fold increase in risk (15 cases vs. 23 controls, OR 3.07, 95% CI 1.35 to 7.00). Other aspects of the reproductive history were not related to risk. In brief, the results of the present study support the hypothesis that, in women, early menarche and greater adult stature may be early predictors of the development of cancer of the pancreas later in life.
| Original language | English |
|---|---|
| Pages (from-to) | 24-29 |
| Number of pages | 6 |
| Journal | International Journal of Cancer |
| Volume | 52 |
| Issue number | 1 |
| Publication status | Published - 1992 |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Anthropometric and reproductive variables and exocrine carcinoma of the pancreas : A population-based case-control study in The Netherlands. / Bueno De Mesquita, H. B.; Maisonneuve, P.; Moerman, C. J.; Walker, A. M.
In: International Journal of Cancer, Vol. 52, No. 1, 1992, p. 24-29.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anthropometric and reproductive variables and exocrine carcinoma of the pancreas
T2 - A population-based case-control study in The Netherlands
AU - Bueno De Mesquita, H. B.
AU - Maisonneuve, P.
AU - Moerman, C. J.
AU - Walker, A. M.
PY - 1992
Y1 - 1992
N2 - During 1984-88 a population-based case-control study was carried out in The Netherlands, in collaboration with the International Agency for Research on Cancer, to examine the possible relationship between aspects of medical history and exocrine pancreatic carcinoma in 176 cases and 487 controls. About 58% of patients were interviewed directly. In women, a significant, positive dose-response effect of height was seen (p-value trend <0.005). Compared with ages 14 or more, women with an early age at menarche, i.e., 11 years or less, had a 3-fold increase in risk (15 cases vs. 23 controls, OR 3.07, 95% CI 1.35 to 7.00). Other aspects of the reproductive history were not related to risk. In brief, the results of the present study support the hypothesis that, in women, early menarche and greater adult stature may be early predictors of the development of cancer of the pancreas later in life.
AB - During 1984-88 a population-based case-control study was carried out in The Netherlands, in collaboration with the International Agency for Research on Cancer, to examine the possible relationship between aspects of medical history and exocrine pancreatic carcinoma in 176 cases and 487 controls. About 58% of patients were interviewed directly. In women, a significant, positive dose-response effect of height was seen (p-value trend <0.005). Compared with ages 14 or more, women with an early age at menarche, i.e., 11 years or less, had a 3-fold increase in risk (15 cases vs. 23 controls, OR 3.07, 95% CI 1.35 to 7.00). Other aspects of the reproductive history were not related to risk. In brief, the results of the present study support the hypothesis that, in women, early menarche and greater adult stature may be early predictors of the development of cancer of the pancreas later in life.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026671448&partnerID=8YFLogxK
M3 - Article
VL - 52
SP - 24
EP - 29
JO - International Journal of Cancer
JF - International Journal of Cancer
SN - 0020-7136
IS - 1
ER -