TY - JOUR
T1 - Anthropometric characteristics of newborns with Prader-Willi syndrome
AU - Salvatoni, Alessandro
AU - Moretti, Alex
AU - Grugni, Graziano
AU - Agosti, Massimo
AU - Azzolini, Sara
AU - Bonaita, Valentina
AU - Cianci, Paola
AU - Corica, Domenico
AU - Crinò, Antonino
AU - Delvecchio, Maurizio
AU - Ferraris, Silvio
AU - Greggio, Nella A.
AU - Iughetti, Lorenzo
AU - Licenziati, Maria R.
AU - Madeo, Simona F.
AU - Nosetti, Luana
AU - Pajno, Roberta
AU - Rutigliano, Irene
AU - Sacco, Michele
AU - Salvatore, Silvia
AU - Scarano, Emanuela
AU - Trifirò, Giuliana
AU - Wasniewska, Malgorzata
PY - 2019/10/1
Y1 - 2019/10/1
N2 - This is a retrospective multicenter nationwide Italian study collecting neonatal anthropometric data of Caucasian subjects with Prader-Willi syndrome (PWS) born from 1988 to 2018. The aim of the study is to provide percentile charts for weight and length of singletons with PWS born between 36 and 42 gestational weeks. We collected the birth weight and birth length of 252 male and 244 female singleton live born infants with both parents of Italian origin and PWS genetically confirmed. Percentile smoothed curves of birth weight and length for gestational age were built through Cole's lambda, mu, sigma method. The data were compared to normal Italian standards. Newborns with PWS showed a lower mean birth weight, by 1/2 kg, and a shorter mean birth length, by 1 cm, than healthy neonates. Females with a 15q11-13 deletion were shorter than those with maternal uniparental maternal disomy of chromosome 15 (p 
AB - This is a retrospective multicenter nationwide Italian study collecting neonatal anthropometric data of Caucasian subjects with Prader-Willi syndrome (PWS) born from 1988 to 2018. The aim of the study is to provide percentile charts for weight and length of singletons with PWS born between 36 and 42 gestational weeks. We collected the birth weight and birth length of 252 male and 244 female singleton live born infants with both parents of Italian origin and PWS genetically confirmed. Percentile smoothed curves of birth weight and length for gestational age were built through Cole's lambda, mu, sigma method. The data were compared to normal Italian standards. Newborns with PWS showed a lower mean birth weight, by 1/2 kg, and a shorter mean birth length, by 1 cm, than healthy neonates. Females with a 15q11-13 deletion were shorter than those with maternal uniparental maternal disomy of chromosome 15 (p 
KW - growth
KW - newborn
KW - percentiles
KW - Prader-Willi
U2 - 10.1002/ajmg.a.61304
DO - 10.1002/ajmg.a.61304
M3 - Article
VL - 179
SP - 2067
EP - 2074
JO - American Journal of Medical Genetics, Part A
JF - American Journal of Medical Genetics, Part A
SN - 1552-4825
IS - 10
ER -