Anthropometric measures, medical history and risk of basal cell carcinoma in an Italian case-control study

Claudio Pelucchi, Luigi Naldi, Anna Di Landro, Carlo La Vecchia

Research output: Contribution to journalArticle

Abstract

Background/Aims: A few epidemiological studies investigated etiological factors for basal cell carcinoma (BCC) other than sunlight exposure and sunburns. Information on anthropometric measures and medical history is scant. Methods: We examined the issue in a case-control study including 528 patients with incident, histologically confirmed BCC and 512 controls hospitalized with acute conditions. Results: Odds ratios (OR) for the highest versus the lowest quartiles were 0.77 for weight, 0.99 for height, 0.87 for body mass index and 0.81 for body surface area. Corresponding estimates for trunk BCC were 0.42, 0.81, 0.50 and 0.47. Subjects with asthma (OR = 0.26) and diabetes mellitus (OR = 0.23) showed a decreased risk of trunk BCC but not face and neck BCC. Conclusion: The inverse relations between trunk, but not face and neck BCC, and obesity, diabetes mellitus and asthma may indirectly reflect the different role of past sunlight exposure to different body locations and variable etiologic pathways for BCCs according to body areas.

Original languageEnglish
Pages (from-to)271-276
Number of pages6
JournalDermatology
Volume216
Issue number3
DOIs
Publication statusPublished - Mar 2008

Keywords

  • Basal cell carcinoma
  • Body mass index
  • Case-control studies
  • Epidemiology
  • Medical history
  • Risk factors

ASJC Scopus subject areas

  • Dermatology

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