Anti-angiogenesis in neuroblastoma

Domenico Ribatti

Research output: Contribution to journalArticle

Abstract

The nature of the angiogenic balance in neuroblastoma is complex, and a spectrum of angiogenesis stimulators and inhibitors have been detected in neuroblastoma tumours. The complex relationships between angiogenic cascade and anti-angiogenic agents in the tumour vascular phase have indicated that anti-angiogenesis can be considered as a strategy for the adjuvant therapy of neuroblastoma. The major goal is to establish if inhibition of angiogenesis is a realistic therapeutic strategy for inhibiting tumour cell dissemination and the formation of metastasis in neuroblastoma.

Original languageEnglish
Pages (from-to)212-221
Number of pages10
JournalCritical Reviews in Oncology/Hematology
Volume86
Issue number3
DOIs
Publication statusPublished - Jun 2013

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Keywords

  • Angiogenesis
  • Anti-angiogenesis
  • Neuroblastoma
  • Tumour growth

ASJC Scopus subject areas

  • Oncology
  • Hematology
  • Geriatrics and Gerontology

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