Abstract
Objective: To evaluate anti-Müllerian hormone (AMH) concentrations and antral follicle counts (AFCs) in the prediction of pregnancy outcomes after controlled ovarian stimulation among women undergoing intrauterine insemination. Methods: A retrospective study included women with unexplained infertility aged 41. years or younger who attended a fertility clinic in Italy between December 2009 and May 2014. Ovarian stimulation was achieved with recombinant follicle-stimulating hormone or highly purified human menopausal gonadotropin. Receiver operating characteristic curves were generated to predict ongoing pregnancy. The primary outcome was the association between AMH/AFC and ongoing pregnancy, and was assessed by logistic regression. Results: Overall, 276 women were included, of whom 43 (15.6%) achieved ongoing pregnancy. Multivariate analysis showed that women with a serum day-3 concentration of AMH higher than 2.3. ng/mL were more likely to have ongoing pregnancy than were those with a concentration lower than 2.3. ng/mL (odds ratio 5.84, 95% confidence interval 2.38-14.31; P
| Original language | English |
|---|---|
| Journal | International Journal of Gynecology and Obstetrics |
| DOIs | |
| Publication status | Accepted/In press - Apr 14 2015 |
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Keywords
- Anti-Müllerian hormone
- Antral follicle count
- Intrauterine insemination
- Ovulation induction
- Prediction
ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
Anti-Müllerian hormone concentrations and antral follicle counts for the prediction of pregnancy outcomes after intrauterine insemination. / Moro, Francesca; Tropea, Anna; Scarinci, Elisa; Leoncini, Emanuele; Boccia, Stefania; Federico, Alex; Alesiani, Ornella; Lanzone, Antonio; Apa, Rosanna.
In: International Journal of Gynecology and Obstetrics, 14.04.2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anti-Müllerian hormone concentrations and antral follicle counts for the prediction of pregnancy outcomes after intrauterine insemination
AU - Moro, Francesca
AU - Tropea, Anna
AU - Scarinci, Elisa
AU - Leoncini, Emanuele
AU - Boccia, Stefania
AU - Federico, Alex
AU - Alesiani, Ornella
AU - Lanzone, Antonio
AU - Apa, Rosanna
PY - 2015/4/14
Y1 - 2015/4/14
N2 - Objective: To evaluate anti-Müllerian hormone (AMH) concentrations and antral follicle counts (AFCs) in the prediction of pregnancy outcomes after controlled ovarian stimulation among women undergoing intrauterine insemination. Methods: A retrospective study included women with unexplained infertility aged 41. years or younger who attended a fertility clinic in Italy between December 2009 and May 2014. Ovarian stimulation was achieved with recombinant follicle-stimulating hormone or highly purified human menopausal gonadotropin. Receiver operating characteristic curves were generated to predict ongoing pregnancy. The primary outcome was the association between AMH/AFC and ongoing pregnancy, and was assessed by logistic regression. Results: Overall, 276 women were included, of whom 43 (15.6%) achieved ongoing pregnancy. Multivariate analysis showed that women with a serum day-3 concentration of AMH higher than 2.3. ng/mL were more likely to have ongoing pregnancy than were those with a concentration lower than 2.3. ng/mL (odds ratio 5.84, 95% confidence interval 2.38-14.31; P
AB - Objective: To evaluate anti-Müllerian hormone (AMH) concentrations and antral follicle counts (AFCs) in the prediction of pregnancy outcomes after controlled ovarian stimulation among women undergoing intrauterine insemination. Methods: A retrospective study included women with unexplained infertility aged 41. years or younger who attended a fertility clinic in Italy between December 2009 and May 2014. Ovarian stimulation was achieved with recombinant follicle-stimulating hormone or highly purified human menopausal gonadotropin. Receiver operating characteristic curves were generated to predict ongoing pregnancy. The primary outcome was the association between AMH/AFC and ongoing pregnancy, and was assessed by logistic regression. Results: Overall, 276 women were included, of whom 43 (15.6%) achieved ongoing pregnancy. Multivariate analysis showed that women with a serum day-3 concentration of AMH higher than 2.3. ng/mL were more likely to have ongoing pregnancy than were those with a concentration lower than 2.3. ng/mL (odds ratio 5.84, 95% confidence interval 2.38-14.31; P
KW - Anti-Müllerian hormone
KW - Antral follicle count
KW - Intrauterine insemination
KW - Ovulation induction
KW - Prediction
UR - http://www.scopus.com/inward/record.url?scp=84957927209&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84957927209&partnerID=8YFLogxK
U2 - 10.1016/j.ijgo.2015.08.021
DO - 10.1016/j.ijgo.2015.08.021
M3 - Article
AN - SCOPUS:84957927209
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
SN - 0020-7292
ER -