A review of the literature was carried out in order to identify those mechanisms responsible for hyperplasia of Enterocromaffin-like cells (ECL) undergoing treatment with anti-secretory drugs. All gastricc acid secretion-inhibiting drugs cause a physiological increase in gastrinemia due to their inhibitory function. ECL hyperplasia is the consequence of the duration of hypergastrinemia. To date no factors responsible for the possible transformation of hyperplasia into carcinoma have yet been identified.
|Translated title of the contribution||Anti-secretory drugs. Hypergastrinemia and ECL hyperplasia|
|Number of pages||6|
|Journal||Minerva Dietologica e Gastroenterologica|
|Publication status||Published - 1991|
ASJC Scopus subject areas