Antiangiogenic and antivascular therapy for cancer

Giulia Taraboletti, Barbara Margosio

Research output: Contribution to journalArticlepeer-review


The great interest in the potential antineoplastic effect of targeting tumor-associated blood vessels has generated an expanding armamentarium of therapeutic tools that include antiangiogenic compounds, aimed at preventing the formation of vessels, and antivascular compounds, targeted to the existing tumor vasculature. Following promising preclinical studies, antiangiogenic drugs have rapidly gained access to clinical trials.

Original languageEnglish
Pages (from-to)378-384
Number of pages7
JournalCurrent Opinion in Pharmacology
Issue number4
Publication statusPublished - Aug 1 2001


  • Antineoplastic therapy
  • Antivascular therapy
  • Cancer Biology
  • Growth factors
  • Inhibitors of angiogenesis
  • Matrix metalloproteinases
  • Pharmacology
  • Tumor angiogenesis
  • Vascular targeting

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Pharmacology


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