Antibacterial activity of methyl aminolevulinate photodynamic therapy in the treatment of a cutaneous ulcer

V. Devirgiliis, V. Panasiti, D. Fioriti, E. Anzivino, A. Bellizzi, M. Cimillo, M. Curzio, L. Melis, V. Roberti, S. Gobbi, P. Lieto, A. G. Richetta, S. Calvieri, F. Chiarini, R. Nicosia, Valeria Pietropaolo

Research output: Contribution to journalArticle

Abstract

We describe a 79-year-old female with a chronic venous ulceration infected by Staphylococcus aureus and Enterococcus faecalis and not responsive to conventional treatments. The patient was treated with Methyl-Aminolaevulinate Photodynamic Therapy (MAL-PDT). After four weeks the cutaneous swabs become negative and we observed a significant clinical improvement. Therefore we suppose that MAL-PDT could represent a valid therapeutic option in the treatment of infected chronic ulcers.

Original languageEnglish
Pages (from-to)793-795
Number of pages3
JournalInternational Journal of Immunopathology and Pharmacology
Volume24
Issue number3
Publication statusPublished - Jul 2011

Keywords

  • Chronic venous ulceration
  • Enterococcus faecalis
  • Methyl-aminolevulinic acid (MAL)
  • Photodynamic therapy (PDT)
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Pharmacology
  • Immunology
  • Immunology and Allergy

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  • Cite this

    Devirgiliis, V., Panasiti, V., Fioriti, D., Anzivino, E., Bellizzi, A., Cimillo, M., Curzio, M., Melis, L., Roberti, V., Gobbi, S., Lieto, P., Richetta, A. G., Calvieri, S., Chiarini, F., Nicosia, R., & Pietropaolo, V. (2011). Antibacterial activity of methyl aminolevulinate photodynamic therapy in the treatment of a cutaneous ulcer. International Journal of Immunopathology and Pharmacology, 24(3), 793-795.