Antibiotic-induced anaphylaxis

Pascal Demoly, Philippe Jean Bousquet, Antonino Romano

Research output: Chapter in Book/Report/Conference proceedingChapter


An antibiotic allergic reaction represents one of the side effects of drugs and is a daily worry for the clinician. If urticaria and maculo-papular eruptions are the most frequent manifestations, then anaphylaxis can occur. The tools allowing a definite diagnosis are validated for some antibiotics and include the following procedures: a thorough clinical history, standardized skin tests, reliable biological tests, and drug provocation tests. When properly performed in specialized centers, a firm diagnosis is often possible and safe alternative medication can be proposed. This is particularly the case for b-lactam antibiotics, considering their wide prescription and utility.

Original languageEnglish
Title of host publicationAnaphylaxis and Hypersensitivity Reactions
PublisherHumana Press
Number of pages12
ISBN (Print)9781603279505
Publication statusPublished - 2011


  • β(beta)-lactams
  • Anaphylaxis
  • Antibiotic allergy
  • Drug allergy/hypersensitivity
  • Provocation tests
  • Skin tests
  • Specific IgE

ASJC Scopus subject areas

  • Medicine(all)


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