Antibiotic-induced anaphylaxis

Pascal Demoly; Philippe Jean Bousquet; Antonino Romano

doi:10.1007/978-1-60327-951-2_10

Antibiotic-induced anaphylaxis

Pascal Demoly, Philippe Jean Bousquet, Antonino Romano

www.irccs.oasi.en.it

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Abstract

An antibiotic allergic reaction represents one of the side effects of drugs and is a daily worry for the clinician. If urticaria and maculo-papular eruptions are the most frequent manifestations, then anaphylaxis can occur. The tools allowing a definite diagnosis are validated for some antibiotics and include the following procedures: a thorough clinical history, standardized skin tests, reliable biological tests, and drug provocation tests. When properly performed in specialized centers, a firm diagnosis is often possible and safe alternative medication can be proposed. This is particularly the case for b-lactam antibiotics, considering their wide prescription and utility.

Original language	English
Title of host publication	Anaphylaxis and Hypersensitivity Reactions
Publisher	Humana Press
Pages	171-182
Number of pages	12
ISBN (Print)	9781603279505
DOIs	https://doi.org/10.1007/978-1-60327-951-2_10
Publication status	Published - 2011

Keywords

β(beta)-lactams
Anaphylaxis
Antibiotic allergy
Drug allergy/hypersensitivity
Provocation tests
Skin tests
Specific IgE

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-1-60327-951-2_10

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AB - An antibiotic allergic reaction represents one of the side effects of drugs and is a daily worry for the clinician. If urticaria and maculo-papular eruptions are the most frequent manifestations, then anaphylaxis can occur. The tools allowing a definite diagnosis are validated for some antibiotics and include the following procedures: a thorough clinical history, standardized skin tests, reliable biological tests, and drug provocation tests. When properly performed in specialized centers, a firm diagnosis is often possible and safe alternative medication can be proposed. This is particularly the case for b-lactam antibiotics, considering their wide prescription and utility.

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KW - Provocation tests

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KW - Specific IgE

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Antibiotic-induced anaphylaxis

Abstract

Keywords

ASJC Scopus subject areas

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