Antibiotic prophylaxis in colorectal surgery

Francesca Rovera, Mario Diurni, Gianlorenzo Dionigi, Luigi Boni, Alberta Ferrari, Giulio Carcano, Renzo Dionigi

Research output: Contribution to journalArticlepeer-review


Nosocomial infections are the most frequent complications observed in surgical patients. In colorectal surgery, the opening of the viscera causes the dissemination into the operative field of microorganisms originating from endogenous sources, increasing the chance of developing postoperative complications. It is reported that without antibiotic prophylaxis, wound infection after colorectal surgery develops in approximately 40% of patients. This percentage decreases to approximately 11% after antibiotic prophylaxis. Specific criteria in the choice of correct antibiotic prophylaxis have to be respected, on the basis of the microorganisms usually found in the surgical site, and on the specific hospital microbiologic epidemiology.

Original languageEnglish
Pages (from-to)787-795
Number of pages9
JournalExpert Review of Anti-Infective Therapy
Issue number5
Publication statusPublished - Oct 2005


  • Antibiotic prophylaxis
  • Colorectal surgery
  • Postoperative complications
  • Surgical site infections

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases


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