Antiblastic chemotherapy in the presence of abdominal aorta aneurysm (AAA): Guidelines

Salvatore Lauro, Gaetano Lanzetta, Emilio Bria, Luciana Trasatti, Alain Gelibter, Aldo Vecchione

Research output: Contribution to journalArticlepeer-review

Abstract

Concominant neoplasm and abdominal aortic aneurysm (AAA) is not a rare clinical association and can pose problems if antiblastic treatment is required. The literature shows lack of consensus owing to the fact that AAA can modify the liquid load and the hemodynamic setting so that chemotherapy toxicily profile becomes important and hydralion overload increases the AAA-breakage risk. We have analyzed the possibility of treatment with a non-critical water load related chemotherapy in these patients, and if it can offer benefit it terms of overall survival (OS) and quality of life (QL). We concluded thatin chemotherapy the presence of AAA does not have to be excluded first, if such critical parameters such as response to chemotherapy AAA-breakage risk vascular and extravascular toxicity do not compromise the OS and QL of the patients.

Original languageEnglish
Pages (from-to)1439-1444
Number of pages6
JournalAnticancer Research
Volume19
Issue number2 B
Publication statusPublished - 1999

Keywords

  • Abdominal aortic aneurysm
  • Chemotherapy
  • Neoplasm

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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