Abstract
Aims: The aim of this study was to investigate whether the shelf-life of diagnostic antibodies is longer than the expiry date on the label. Methods and results: Four independent laboratories tested a small number of diagnostic antibodies kept at +4°C for 12-26 years, and found them to work perfectly on routine histology sections. Conclusions: Diagnostic antibodies may have a workable half-life in excess of 10 years, and the emphasis on performance should shift to the preservation of antigenic targets in the tissue.
Original language | English |
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Pages (from-to) | 869-876 |
Number of pages | 8 |
Journal | Histopathology |
Volume | 63 |
Issue number | 6 |
DOIs | |
Publication status | Published - Dec 2013 |
Keywords
- Antibody
- Expiry date
- Immunohistochemistry
ASJC Scopus subject areas
- Histology
- Pathology and Forensic Medicine