We used first- and second-generation assays such as Ortho I, Ortho 2 and 4-RIBA to define prevalence and nsk factors for anti-HCV antibodies in haemodialysed patients. Forty-nine (24%) subjects were found to be anti-HCV positive. Anti-HCV positiv ity was related to duration of dialysis and past or current elevations of GOT and GPT; the frequency of transfused patients was greater in HCV-positive than in HCV-negative subjects; there were 31 patients (pre valence of 20%) with anti-HCV antibodies among non-transfused patients. These findings show that, tested by second-generation assays, HCV infection is detected more than twice as commonly in haemodia lysis patients and may be responsible for a significant proportion of liver disease in this clinical setting Acquisition of hepatitis C virus by dialysis patients is not only through blood transfusions but also secondary to hepatitis C virus presence within the unit itself.
|Number of pages||4|
|Journal||Nephrology Dialysis Transplantation|
|Publication status||Published - 1993|
- Hepatitis C virus
- Transaminase levels
ASJC Scopus subject areas