Abstract
We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.
| Original language | English |
|---|---|
| Pages (from-to) | 68-70 |
| Number of pages | 3 |
| Journal | Acta Neurologica |
| Volume | 12 |
| Issue number | 1 |
| Publication status | Published - Feb 1990 |
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ASJC Scopus subject areas
- Clinical Neurology
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Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients. / Martino, G. V.; Grimaldi, L. M.; Moiola, L.; Cichero, P.; Ieri, R.; Bonini, P. A.
In: Acta Neurologica, Vol. 12, No. 1, 02.1990, p. 68-70.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients.
AU - Martino, G. V.
AU - Grimaldi, L. M.
AU - Moiola, L.
AU - Cichero, P.
AU - Ieri, R.
AU - Bonini, P. A.
PY - 1990/2
Y1 - 1990/2
N2 - We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.
AB - We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.
UR - http://www.scopus.com/inward/record.url?scp=0025380346&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025380346&partnerID=8YFLogxK
M3 - Article
VL - 12
SP - 68
EP - 70
JO - Acta Neurologica
JF - Acta Neurologica
SN - 0001-6276
IS - 1
ER -