Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients.

G. V. Martino; L. M. Grimaldi; L. Moiola; P. Cichero; R. Ieri; P. A. Bonini

Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients.

G. V. Martino, L. M. Grimaldi, L. Moiola, P. Cichero, R. Ieri, P. A. Bonini

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.

Original language	English
Pages (from-to)	68-70
Number of pages	3
Journal	Acta Neurologica
Volume	12
Issue number	1
Publication status	Published - Feb 1990

ASJC Scopus subject areas

Clinical Neurology

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title = "Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients.",

abstract = "We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.",

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T1 - Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients.

AU - Martino, G. V.

AU - Grimaldi, L. M.

AU - Moiola, L.

AU - Cichero, P.

AU - Ieri, R.

AU - Bonini, P. A.

PY - 1990/2

Y1 - 1990/2

N2 - We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.

AB - We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.

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Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients.

Abstract

ASJC Scopus subject areas

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