Abstract
We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.
| Original language | English |
|---|---|
| Pages (from-to) | 68-70 |
| Number of pages | 3 |
| Journal | Acta Neurologica |
| Volume | 12 |
| Issue number | 1 |
| Publication status | Published - Feb 1990 |
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ASJC Scopus subject areas
- Clinical Neurology
Cite this
Martino, G. V., Grimaldi, L. M., Moiola, L., Cichero, P., Ieri, R., & Bonini, P. A. (1990). Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients. Acta Neurologica, 12(1), 68-70.