Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients.

G. V. Martino, L. M. Grimaldi, L. Moiola, P. Cichero, R. Ieri, P. A. Bonini

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Abstract

We have measured the levels of antibody (ab) against different Epstein-Barr virus (EBV) antigens in 10 AIDS patients, 7 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 20 control subjects. We found comparable serum levels of anti-EBV ab between AIDS patients, HAM/TSP patients and control subjects. By contrast, anti-EBV ab were present in the large majority of CSF from AIDS patients (70%) and HAM/TSP patients (60%) but only in 15% of control group. Our results support a synergistic role of EBV in retroviral infections of the central nervous system.

Original languageEnglish
Pages (from-to)68-70
Number of pages3
JournalActa Neurologica
Volume12
Issue number1
Publication statusPublished - Feb 1990

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ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Martino, G. V., Grimaldi, L. M., Moiola, L., Cichero, P., Ieri, R., & Bonini, P. A. (1990). Antibody against EBV in CSF from HIV-1 and HTLV-I infected patients. Acta Neurologica, 12(1), 68-70.