Anticancer treatment and fertility effects. Literature review

F. Tomao, E. Miele, G. P. Spinelli, S. Tomao

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Chemotherapic regimens include mutagenic agents. The risk for reproductive abnormalities is increased in patients treated with such antiblastic drugs, mostly before or during their fertile period. The effect of chemotherapy on male and female gonadal function is related to the type of used agent and their cumulative doses. Other antineoplastic approaches, such as radiation therapy or hormonal therapy, can also negatively influence fertility. In the evaluation of quality of life of people affected by malignancies, infertility is considered an important issue. For this reason a large number of options have been tested as fertility preserving strategies - many are promising but still at an experimental stage.

Original languageEnglish
Pages (from-to)475-481
Number of pages7
JournalJournal of Experimental and Clinical Cancer Research
Volume25
Issue number4
Publication statusPublished - Dec 2006

Fingerprint

Fertility Agents
Fertility
Fertile Period
Antineoplastic Agents
Infertility
Radiotherapy
Quality of Life
Drug Therapy
Therapeutics
Pharmaceutical Preparations
Neoplasms

Keywords

  • Anticancer treatment
  • Fertility

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Tomao, F., Miele, E., Spinelli, G. P., & Tomao, S. (2006). Anticancer treatment and fertility effects. Literature review. Journal of Experimental and Clinical Cancer Research, 25(4), 475-481.

Anticancer treatment and fertility effects. Literature review. / Tomao, F.; Miele, E.; Spinelli, G. P.; Tomao, S.

In: Journal of Experimental and Clinical Cancer Research, Vol. 25, No. 4, 12.2006, p. 475-481.

Research output: Contribution to journalArticle

Tomao, F, Miele, E, Spinelli, GP & Tomao, S 2006, 'Anticancer treatment and fertility effects. Literature review', Journal of Experimental and Clinical Cancer Research, vol. 25, no. 4, pp. 475-481.
Tomao, F. ; Miele, E. ; Spinelli, G. P. ; Tomao, S. / Anticancer treatment and fertility effects. Literature review. In: Journal of Experimental and Clinical Cancer Research. 2006 ; Vol. 25, No. 4. pp. 475-481.
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