Abstract
Chemotherapic regimens include mutagenic agents. The risk for reproductive abnormalities is increased in patients treated with such antiblastic drugs, mostly before or during their fertile period. The effect of chemotherapy on male and female gonadal function is related to the type of used agent and their cumulative doses. Other antineoplastic approaches, such as radiation therapy or hormonal therapy, can also negatively influence fertility. In the evaluation of quality of life of people affected by malignancies, infertility is considered an important issue. For this reason a large number of options have been tested as fertility preserving strategies - many are promising but still at an experimental stage.
| Original language | English |
|---|---|
| Pages (from-to) | 475-481 |
| Number of pages | 7 |
| Journal | Journal of Experimental and Clinical Cancer Research |
| Volume | 25 |
| Issue number | 4 |
| Publication status | Published - Dec 2006 |
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Keywords
- Anticancer treatment
- Fertility
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Anticancer treatment and fertility effects. Literature review. / Tomao, F.; Miele, E.; Spinelli, G. P.; Tomao, S.
In: Journal of Experimental and Clinical Cancer Research, Vol. 25, No. 4, 12.2006, p. 475-481.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anticancer treatment and fertility effects. Literature review
AU - Tomao, F.
AU - Miele, E.
AU - Spinelli, G. P.
AU - Tomao, S.
PY - 2006/12
Y1 - 2006/12
N2 - Chemotherapic regimens include mutagenic agents. The risk for reproductive abnormalities is increased in patients treated with such antiblastic drugs, mostly before or during their fertile period. The effect of chemotherapy on male and female gonadal function is related to the type of used agent and their cumulative doses. Other antineoplastic approaches, such as radiation therapy or hormonal therapy, can also negatively influence fertility. In the evaluation of quality of life of people affected by malignancies, infertility is considered an important issue. For this reason a large number of options have been tested as fertility preserving strategies - many are promising but still at an experimental stage.
AB - Chemotherapic regimens include mutagenic agents. The risk for reproductive abnormalities is increased in patients treated with such antiblastic drugs, mostly before or during their fertile period. The effect of chemotherapy on male and female gonadal function is related to the type of used agent and their cumulative doses. Other antineoplastic approaches, such as radiation therapy or hormonal therapy, can also negatively influence fertility. In the evaluation of quality of life of people affected by malignancies, infertility is considered an important issue. For this reason a large number of options have been tested as fertility preserving strategies - many are promising but still at an experimental stage.
KW - Anticancer treatment
KW - Fertility
UR - http://www.scopus.com/inward/record.url?scp=33846471011&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33846471011&partnerID=8YFLogxK
M3 - Article
C2 - 17310836
AN - SCOPUS:33846471011
VL - 25
SP - 475
EP - 481
JO - Journal of Experimental and Clinical Cancer Research
JF - Journal of Experimental and Clinical Cancer Research
SN - 0392-9078
IS - 4
ER -