Profilassi antitrombotica in donne con diagnosi di trombofilia e precedenti complicanze ostetriche

Translated title of the contribution: Anticoagulant prophylaxis in women affected by thrombophilia and previous obstetric complications

E. Grandone, D. Colaizzo, P. Vergura, G. Tiscia, E. Chinni, M. Tomaiuolo, M. Margaglione

Research output: Contribution to journalArticle

Abstract

Pregnancy is a condition of excessive clotting due to a decrease of some coagulation factors and a reduction of anticoagulant proteins, such as protein S. It is known that the causes of congenital or acquired thrombophilia may be associated with an increased risk of venous thromboembolism during pregnancy and/or obstetric complications, such early or late fetal loss, intrauterine fetal deaths, pre-eclampsia, fetal growth restriction. During pregnancy the use of a prophylaxis with antithrombotic drugs is considered at present a promising opportunity to significantly reduce the prevalence of thromboembolic complications, improving maternal and fetal outcomes. This article is a review to most recent evidence of pregnant anticoagulant prophylaxis in women with previous thromboembolic events.

Translated title of the contributionAnticoagulant prophylaxis in women affected by thrombophilia and previous obstetric complications
Original languageItalian
Pages (from-to)431-436
Number of pages6
JournalMinerva Ginecologica
Volume60
Issue number5
Publication statusPublished - Oct 2008

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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