We report four disabled patients with symptomatic epilepsies who were treated with VPA from the age of 5 months, 3, 5 and 5 years respectively and who developed multiple defects of the proximal renal tubules. Fanconi syndrome appears to be a rare but severe consequence of VPA therapy. Therefore patients, especially children with neurological impairments, should be checked for the possible development of VPA induced Fanconi syndrome.
|Translated title of the contribution||Antiepileptic therapy with Valproic acid and renal adverse effects|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Jul 2004|
ASJC Scopus subject areas
- Clinical Neurology