Trattamento con Valproato di sodio ed effetti indesiderati nefrologici

Translated title of the contribution: Antiepileptic therapy with Valproic acid and renal adverse effects

C. Zucca, L. Radice, A. Bettinelli

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report four disabled patients with symptomatic epilepsies who were treated with VPA from the age of 5 months, 3, 5 and 5 years respectively and who developed multiple defects of the proximal renal tubules. Fanconi syndrome appears to be a rare but severe consequence of VPA therapy. Therefore patients, especially children with neurological impairments, should be checked for the possible development of VPA induced Fanconi syndrome.

Original languageItalian
Pages (from-to)187-188
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number125-126
Publication statusPublished - Jul 2004

Fingerprint

Fanconi Syndrome
Valproic Acid
Anticonvulsants
Kidney
Proximal Kidney Tubule
Epilepsy
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Trattamento con Valproato di sodio ed effetti indesiderati nefrologici. / Zucca, C.; Radice, L.; Bettinelli, A.

In: Bollettino - Lega Italiana contro l'Epilessia, No. 125-126, 07.2004, p. 187-188.

Research output: Contribution to journalArticle

@article{2c2818834e024440accb52189fb29eff,
title = "Trattamento con Valproato di sodio ed effetti indesiderati nefrologici",
abstract = "We report four disabled patients with symptomatic epilepsies who were treated with VPA from the age of 5 months, 3, 5 and 5 years respectively and who developed multiple defects of the proximal renal tubules. Fanconi syndrome appears to be a rare but severe consequence of VPA therapy. Therefore patients, especially children with neurological impairments, should be checked for the possible development of VPA induced Fanconi syndrome.",
keywords = "Fanconi syndrome, Renal tubular function, Sodium valproate",
author = "C. Zucca and L. Radice and A. Bettinelli",
year = "2004",
month = "7",
language = "Italian",
pages = "187--188",
journal = "Bollettino - Lega Italiana contro l'Epilessia",
issn = "0394-560X",
publisher = "Lega Italiana contro l'Epilessia",
number = "125-126",

}

TY - JOUR

T1 - Trattamento con Valproato di sodio ed effetti indesiderati nefrologici

AU - Zucca, C.

AU - Radice, L.

AU - Bettinelli, A.

PY - 2004/7

Y1 - 2004/7

N2 - We report four disabled patients with symptomatic epilepsies who were treated with VPA from the age of 5 months, 3, 5 and 5 years respectively and who developed multiple defects of the proximal renal tubules. Fanconi syndrome appears to be a rare but severe consequence of VPA therapy. Therefore patients, especially children with neurological impairments, should be checked for the possible development of VPA induced Fanconi syndrome.

AB - We report four disabled patients with symptomatic epilepsies who were treated with VPA from the age of 5 months, 3, 5 and 5 years respectively and who developed multiple defects of the proximal renal tubules. Fanconi syndrome appears to be a rare but severe consequence of VPA therapy. Therefore patients, especially children with neurological impairments, should be checked for the possible development of VPA induced Fanconi syndrome.

KW - Fanconi syndrome

KW - Renal tubular function

KW - Sodium valproate

UR - http://www.scopus.com/inward/record.url?scp=22944453738&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=22944453738&partnerID=8YFLogxK

M3 - Articolo

SP - 187

EP - 188

JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

SN - 0394-560X

IS - 125-126

ER -