Antifungal lock therapy with combined 70% ethanol and micafungin in a critically ill infant

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Abstract

So-called lock therapy, consisting of high concentrations of antimicrobials instilled into the lumen of the catheter, has been suggested avoid central venous catheter removal during fungal infection. We report a baby who developed catheter-related candidemia. Systemic antifungal treatment did not resolve the candidemia. Lock therapy with 0.3 mL of ethanol 70% and micafungin sodium 5 mg/L was added to the therapy, and blood cultures became sterile.

Original languageEnglish
Pages (from-to)419-420
Number of pages2
JournalPediatric Infectious Disease Journal
Volume33
Issue number4
DOIs
Publication statusPublished - 2014

Keywords

  • Candidemia
  • Central venous catheter
  • Lock therapy
  • Micafungin
  • Neonate

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)
  • Medicine(all)

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