Antifungal susceptibility testing: Comparative evaluation of two methods

M. Perduca; E. Marangoni; A. Guanziroli; E. Romero; G. Filice

Antifungal susceptibility testing: Comparative evaluation of two methods

M. Perduca, E. Marangoni, A. Guanziroli, E. Romero, G. Filice

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

One hundred and two specimens from 94 immunosuppressed hosts were investigated for fungal infections. Fourteen fungal species belonging to five genera were isolated. The most frequent genus was Candida (78%) the most frequent species was Candida albicans (50%). These strains were tested in vitro with amphotericin B, 5-fluorocytosine, nystatin, miconazole nitrate, econazole and ketoconazole by two methods: Kirby-Bauer and ATB fungus. Overlapping results were obtainesd in only 11 fungal strains. A complete concordance was observed in amphotericin B sensitivity (100%). The major discrepancies were found in imidazoles which demonstrated a minor activity with ATB fungus method.

Original language	English
Pages (from-to)	9-13
Number of pages	5
Journal	Mediterranean Journal of Infectious and Parasitic Diseases
Volume	10
Issue number	1
Publication status	Published - 1995

Keywords

ATB fungus
azoles
fungal infections
immunocompromised hosts
Kirby-Bauer method
polyenes

ASJC Scopus subject areas

Microbiology (medical)

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abstract = "One hundred and two specimens from 94 immunosuppressed hosts were investigated for fungal infections. Fourteen fungal species belonging to five genera were isolated. The most frequent genus was Candida (78%) the most frequent species was Candida albicans (50%). These strains were tested in vitro with amphotericin B, 5-fluorocytosine, nystatin, miconazole nitrate, econazole and ketoconazole by two methods: Kirby-Bauer and ATB fungus. Overlapping results were obtainesd in only 11 fungal strains. A complete concordance was observed in amphotericin B sensitivity (100%). The major discrepancies were found in imidazoles which demonstrated a minor activity with ATB fungus method.",

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AU - Perduca, M.

AU - Marangoni, E.

AU - Guanziroli, A.

AU - Romero, E.

AU - Filice, G.

PY - 1995

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AB - One hundred and two specimens from 94 immunosuppressed hosts were investigated for fungal infections. Fourteen fungal species belonging to five genera were isolated. The most frequent genus was Candida (78%) the most frequent species was Candida albicans (50%). These strains were tested in vitro with amphotericin B, 5-fluorocytosine, nystatin, miconazole nitrate, econazole and ketoconazole by two methods: Kirby-Bauer and ATB fungus. Overlapping results were obtainesd in only 11 fungal strains. A complete concordance was observed in amphotericin B sensitivity (100%). The major discrepancies were found in imidazoles which demonstrated a minor activity with ATB fungus method.

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KW - polyenes

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