Antifungal susceptibility testing: Comparative evaluation of two methods

M. Perduca, E. Marangoni, A. Guanziroli, E. Romero, G. Filice

Research output: Contribution to journalArticlepeer-review

Abstract

One hundred and two specimens from 94 immunosuppressed hosts were investigated for fungal infections. Fourteen fungal species belonging to five genera were isolated. The most frequent genus was Candida (78%) the most frequent species was Candida albicans (50%). These strains were tested in vitro with amphotericin B, 5-fluorocytosine, nystatin, miconazole nitrate, econazole and ketoconazole by two methods: Kirby-Bauer and ATB fungus. Overlapping results were obtainesd in only 11 fungal strains. A complete concordance was observed in amphotericin B sensitivity (100%). The major discrepancies were found in imidazoles which demonstrated a minor activity with ATB fungus method.

Original languageEnglish
Pages (from-to)9-13
Number of pages5
JournalMediterranean Journal of Infectious and Parasitic Diseases
Volume10
Issue number1
Publication statusPublished - 1995

Keywords

  • ATB fungus
  • azoles
  • fungal infections
  • immunocompromised hosts
  • Kirby-Bauer method
  • polyenes

ASJC Scopus subject areas

  • Microbiology (medical)

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