Abstract
The various antihypertensive regimens have varying effects on glucose metabolism and the development of diabetes mellitus. Recent large hypertension trials have shown great differences in the development of new-onset diabetes among antihypertensive drug therapies. The incidence of diabetes is unchanged or increased by thiazide diuretics and β-adrenergic blockers, and unchanged or decreased by angiotensin-converting enzyme inhibitors, calcium channel blockers, and angiotensin-receptor blockers. The differences in new-onset diabetes mellitus have not influenced the outcome of cardiovascular mortality and morbidity in all of the large clinical trials, but drug-induced diabetes among hypertensive patients is known to carry the same cardiovascular risk as that seen in patients with previously known diabetes; however, it might take years for the increased risk to become apparent.
| Original language | English |
|---|---|
| Pages (from-to) | 298-303 |
| Number of pages | 6 |
| Journal | Current Hypertension Reports |
| Volume | 7 |
| Issue number | 4 |
| Publication status | Published - Aug 2005 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
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Antihypertensive treatment and new-onset diabetes mellitus. / Aksnes, Tonje Amb; Reims, Henrik M.; Kjeldsen, Sverre E.; Mancia, Giuseppe.
In: Current Hypertension Reports, Vol. 7, No. 4, 08.2005, p. 298-303.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antihypertensive treatment and new-onset diabetes mellitus
AU - Aksnes, Tonje Amb
AU - Reims, Henrik M.
AU - Kjeldsen, Sverre E.
AU - Mancia, Giuseppe
PY - 2005/8
Y1 - 2005/8
N2 - The various antihypertensive regimens have varying effects on glucose metabolism and the development of diabetes mellitus. Recent large hypertension trials have shown great differences in the development of new-onset diabetes among antihypertensive drug therapies. The incidence of diabetes is unchanged or increased by thiazide diuretics and β-adrenergic blockers, and unchanged or decreased by angiotensin-converting enzyme inhibitors, calcium channel blockers, and angiotensin-receptor blockers. The differences in new-onset diabetes mellitus have not influenced the outcome of cardiovascular mortality and morbidity in all of the large clinical trials, but drug-induced diabetes among hypertensive patients is known to carry the same cardiovascular risk as that seen in patients with previously known diabetes; however, it might take years for the increased risk to become apparent.
AB - The various antihypertensive regimens have varying effects on glucose metabolism and the development of diabetes mellitus. Recent large hypertension trials have shown great differences in the development of new-onset diabetes among antihypertensive drug therapies. The incidence of diabetes is unchanged or increased by thiazide diuretics and β-adrenergic blockers, and unchanged or decreased by angiotensin-converting enzyme inhibitors, calcium channel blockers, and angiotensin-receptor blockers. The differences in new-onset diabetes mellitus have not influenced the outcome of cardiovascular mortality and morbidity in all of the large clinical trials, but drug-induced diabetes among hypertensive patients is known to carry the same cardiovascular risk as that seen in patients with previously known diabetes; however, it might take years for the increased risk to become apparent.
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UR - http://www.scopus.com/inward/citedby.url?scp=24944580949&partnerID=8YFLogxK
M3 - Article
C2 - 16061050
AN - SCOPUS:24944580949
VL - 7
SP - 298
EP - 303
JO - Current Hypertension Reports
JF - Current Hypertension Reports
SN - 1522-6417
IS - 4
ER -