TY - JOUR
T1 - Antimicrobial activity of a formulation for the low temperature disinfection of critical and semi-critical medical equipment and surfaces
AU - Raffo, Paolo
AU - Salliez, A. C.
AU - Collignon, Christian
AU - Clementi, Massimo
PY - 2007/10
Y1 - 2007/10
N2 - The antimicrobial activity of the disinfectant formulation UMONIUM 38 (Isopropyl-tridecyl-dimethyl-ammonium; Huckert's International, Nivelles, Belgium) planned for the low temperature disinfection of critical and semi-critical medical equipment and surfaces was evaluated under clean and dirty experimental conditions (high and low concentrations of organic material). The formulation was obtained by a synergic combination of three different active compounds, two alcohols and a quaternary ammonium. The anti-mycobacterial (Mycobacterium avium and Mycobactenum terrae), and antiviral (Poliovirus type 1, Adenovirus type 5, hepatitis B virus, and human immunodeficiency virus type 1) activities of this formulation were addressed using suspension assays. In addition, surface assays were also used to test the antibacterial (Pseudomonas aeruginosa, Eschenchia coli, Staphylococcus aureus, Enterococcus hirae) and antimycotic (Candida albicans and Aspergillus niger) activities. The data document the dynamics of the antimicrobial activity under in vitro controlled conditions and highlight the relatively low influence of organic material on its activity.
AB - The antimicrobial activity of the disinfectant formulation UMONIUM 38 (Isopropyl-tridecyl-dimethyl-ammonium; Huckert's International, Nivelles, Belgium) planned for the low temperature disinfection of critical and semi-critical medical equipment and surfaces was evaluated under clean and dirty experimental conditions (high and low concentrations of organic material). The formulation was obtained by a synergic combination of three different active compounds, two alcohols and a quaternary ammonium. The anti-mycobacterial (Mycobacterium avium and Mycobactenum terrae), and antiviral (Poliovirus type 1, Adenovirus type 5, hepatitis B virus, and human immunodeficiency virus type 1) activities of this formulation were addressed using suspension assays. In addition, surface assays were also used to test the antibacterial (Pseudomonas aeruginosa, Eschenchia coli, Staphylococcus aureus, Enterococcus hirae) and antimycotic (Candida albicans and Aspergillus niger) activities. The data document the dynamics of the antimicrobial activity under in vitro controlled conditions and highlight the relatively low influence of organic material on its activity.
KW - Antimicrobial activity
KW - Low-temperature disinfection
KW - Synergic compounds
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UR - http://www.scopus.com/inward/citedby.url?scp=36549017052&partnerID=8YFLogxK
M3 - Article
C2 - 18080683
AN - SCOPUS:36549017052
VL - 30
SP - 463
EP - 469
JO - New Microbiologica
JF - New Microbiologica
SN - 1121-7138
IS - 4
ER -